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This film explores one of the principal causes of cognitive decline in Alzheimer's disease—the toxic beta-amyloid protein. It also looks at an experimental vaccine on the front lines of research that is attempting to use the body's own immune system to fight the disease.

We don't have an overview translated in English. Help us expand our database by adding one.

We don't have an overview translated in English. Help us expand our database by adding one.

Is Alzheimer's inherited? What is my risk? With two of the international leaders in the field, we answer these questions and learn about the role genetics plays in the development of drugs to prevent the disease.

We don't have an overview translated in English. Help us expand our database by adding one.

We don't have an overview translated in English. Help us expand our database by adding one.

We don't have an overview translated in English. Help us expand our database by adding one.

We don't have an overview translated in English. Help us expand our database by adding one.

We don't have an overview translated in English. Help us expand our database by adding one.

We don't have an overview translated in English. Help us expand our database by adding one.

We don't have an overview translated in English. Help us expand our database by adding one.

We don't have an overview translated in English. Help us expand our database by adding one.

We don't have an overview translated in English. Help us expand our database by adding one.

We don't have an overview translated in English. Help us expand our database by adding one.

This verité documentary profiles seven people living with the disease, each in an advancing state of dementia, from its earliest detectable changes through death. "We wanted to capture a sense of what it was to be inside the disease," explains Shari Cookson. "Our plan was to show the progression of the illness through several stories along the way." But as Nick Doob points out: "There's nothing clear cut about it. The course of the disease is different from person to person." Adds Cookson: "They say if you've seen one person with Alzheimer's...you've seen one person with Alzheimer's."

There are currently 10 million Americans providing 8.5 billion hours of unpaid care to people with Alzheimer's disease or other dementias, according to an estimate from the Alzheimer's Association. Seventy percent of people with Alzheimer's live at home, cared for by family and friends. As Bill Couturié explains: "Not only is it very expensive to pay for care in a nursing home, but the patient is someone you love a lot - a mother, father, spouse. Someone who has taken care of you, and so it's only natural to want to take care of them." Alzheimer's can take a great toll on the physical and emotional well-being not just of the patient, but of the caregiver as well. "It's not uncommon for the caregiver to die before the patient. It's a 24/7 job and often the caregiver has no help.

This film tells five stories of children, ages 6-15, who are coping with grandfathers or grandmothers suffering from Alzheimer's disease. Maria Shriver provides commentary and delivers valuable "lessons" for the kids, urging them not to blame themselves for what their grandparents do or say. "We are all children of Alzheimer's," says Shriver, sympathetically making it clear that "if it's too painful to visit, you don't have to go."