The Red Guy is sick of being foiled by Super Cow, so he opens up a laundrimat for super heroes, in hope to find out who she really is. It doesn't work, so he goes to Cow and Chicken's house, and kidnaps Cow. Chicken then goes to the rescue as Super Cow for her.

Cow, Chicken, Flem, and Earl try out for the school's sumo wrestling team. For being big and fat, Cow is the new team member. Soon, everyone fears her, and she feels degected, but it benefits Chicken, because now no one will beat him up.

Cow, Chicken, Mom, and Dad go on a safari in Africa, where they run out of gas. Cow and Chicken then find themselves at the mercy of laughing hyenas, and man-eating giraffes. Super Cow comes to the rescue, only to find that she has actually been defeated by the Grizzly Beaver, who has eaten the giraffe, who has eaten Chicken.

The Red Guy sneaks a crow egg under Chicken's covers while he sleeps. The next morning, Cow and Chicken find the egg, and Chicken comes to the conclusion that he is actually a girl. So, it's egg sitting for Cow and Chicken, until the egg hatches and a baby crow comes out. Now Chicken comes to the conclusion that he isn't even a chicken.

The Red Guy is depressed because no one will play with him. After seeing Cow has Crabs the Warthog, he wants to play with her because he has Crabs's doll house. When he askes to play with Cow, she tells him not if he was the last man on earth. With that he locks the entire world in a trailer, and is the last man standing: but Cow still won't play with him.

Cow is depressed because she has no friends: until she finds a fly in her room and befriends it. Pretty soon she and the fly are inseperable: until Chicken, Mom and Dad call in the fly exterminator.

Cow and Chicken are taking a trip all by themselves. Their taking an airplane. Once Chicken sees the actual plain, he starts to have anxiety attacks and believes that flying is a dangerous way to travel.

Chicken refuses to take bath, so he just sits there in the empty tub, while Cow, Mom, and Dad try to make him take a bath so they can use the toilet.

Chicken tells Cow that she's not artistic, so she in return, sculpts a seal out of a stick of chewing gum, and an entire machine full of bubblegum balls. Cow wishes that her chewing gum seal, whom she names Chachi, was real. Suddenly, a wishing star grants her wish, and Chachi is a real, miserable, ho-hum seal.

Cow and Chicken get a visit from their cousin, Black Sheep (who really is in both terms). While Mom and Dad run away, Cow and Chicken try to make Black Sheep feel at home, but when he compliments Flem and Earl in scientific terms, they assume that Black Sheep is a dangerous criminal. Cow tries to help Black Sheep, who everyone changes their minds about, after he saves a woman's life from a heart attack.

Cow and Chicken are devastated when Mom and Dad suddenly announce that their moving. Cow and Chicken start reminising about their favorite memories from the only home they ever lived in, from their first puppy, to their first Christmas. The Red Guy, Flem and Earl are also devastated when Cow and Chicken are moving. Once the truck is loaded, Cow and Chicken discover that they are only moving to an identical house next door. When asked why, Dad replies ""our old house was infested with ants.""

Sick of their everyday life of being squirted with milk, Cow's favorite toys: Crabs the Warthog Doll, Piles the Beaver Doll, and Manure the Bear decide to run away to find their original owner. After reading Manure's tag that says ""Made In Hong Kong"", they assume their original owner is a maiden named Hong Kong, and set out on a quest to find her.

It's almost arbor day, and Mom and Dad are feeding their pet piggy pennies so they can crack him open on arbor day. Meanwhile, Cow and Chicken are craving ice cream, and try to chase down the ice cream man (Red Guy).

Cow and Chicken wait outside the hardware store while Dad shops. Chicken is dying to ride the fighter jet plane ride. When Cow finally lends Chicken a quarter, The Red Guy takes the ride away. Chicken then stows-away on his truck, to ride the plane, but has to plug it up. Once at the gas station, he buys 20 extension cords, but the owner unplugs them. In the end, Chicken discovers that Dad actually collects those kind of rides.

It's ""Bring Your Kids to Work Day"", so Dad does just that. Dad's job is guarding the government's money. When he has to appear at a sudden confernce, he leaves Cow and Chicken in his office. Red Guy, who is now a Canadian Mounty Police, finds them, and begins to stalk them, until they surrender.

Dad loves shopping for Mom's stuff. He runs off to get a manicure for her, while Cow and Chicken pay for the other items. The censors go off when Cow passes through, so Red Guy, as a mall cop, chases Cow and Chicken all over the store. Cow learns that the censors have been broken for weeks. Red Guy walks through, and is arrest by the REAL mall cops.