Luffy gets the chance to catch up with his old friend Coby, Nami does some serious snooping, and Robin is paid a chilling visit from a terrifying face from her past.

Brook tells Luffy that he is glad to be alive and asks if he can join the crew, which Luffy approves of. All the Straw Hats are shocked by this, except for Zoro, who is sleeping, and Robin, who knew Luffy would accept him no matter what, but they nevertheless welcome him to the crew. Two days later, Usopp and Franky make a grave for the dead Rumbar Pirates, and Zoro lays the broken Yubashiri at the grave. Nami gets a Vivre Card from Lola, which points the way to Lola's mother, a pirate in the New World. Luffy takes out the piece of paper he received from Ace, which is also a Vivre Card, and learns that as it is burning and shrinking, Ace's life is in danger. Believing that Ace can get out of trouble on his own, Luffy decides to head onward rather than go to rescue him, and the Straw Hats sail away from Thriller Bark. As the Luffy and his crew sail away, three enormous and mysterious figure appears in the fog, looking over Thriller Bark.

Whitebeard orders his men to help Luffy clear a path to the execution scaffold, but someone close to the Rubber-man rises up to derail the rescue mission at the last second!

Luffy and Katakuri are locked in a duel to end all duels! Their powers ensure that each blow could be the last! Luffy must rely on his training, let all his thoughts out, and keep pushing on! Meanwhile, Sanji is about to land at Cacao Island!

Luffy and Zoro fight against Hawkins' men. Hawkins eventually steps in and displays his powers to them. Komachiyo grabs Luffy and Zoro and runs from the battle, but Hawkins pursues them.

Holdem continues to taunt Luffy's group while holding Tama hostage, threatening to chew her up with Kamijiro. Kiku warns Luffy against attacking Holdem as Kuri is ruled by Jack, and he will destroy Bakura Town if they fight back. Speed arrived with the Treasure ship of food from Paradise Farm. Luffy ordered Zoro to steal the food cart, which he did with Kiku's help. Luffy proceed to punch Kamijiro and rescue Tama. When he saw the injuries on Tama's cheek from being pulled by Holdem with a pincer, he flew into a rage and punched Holdem with Red Hawk, where Tama see Ace in Luffy.

Right after the destruction of Oden Castle, Luffy enters a furious battle with Kaido.

At the Excavation Labor Camp in Udon, Luffy tries to save Old Man Hyo and stands up to Vice Warden Daifuku and Warden Babanuki with his physical strength weakened by the Sea Prism Stone cuffs. Then when a Lead Performer of the Animal Kingdom Pirates, Queen the Plague, comes to the camp, Luffy makes an escape!

After Udon is conquered, Chopper tends to Luffy and works to develop a cure for his condition. Luffy asks Kid to join the fight against Kaido, but Kid rejects his offer and leaves Udon with Killer. After finding out that Luffy is a pirate, the prisoners distrust him, but Momonosuke speaks to them and convinces them to join the cause to liberate Wano Country. Elsewhere, Ashura Doji reveals to Kin'emon and Inuarashi that he had comrades who were too impatient to wait for the Kozuki Family to return and died when they tried to fight Kaido. Afterwards, Ashura comes around and decides to rejoin Kin'emon.

Oden transforms the wild land of Kuri into a habitable region and is made Daimyo over it. Then he meets Kawamatsu the Kappa and the two Minks, Dogstorm and Cat Viper, who become his followers like the others. Kin’emon and the other vassals are scolded by Yasuie when they try to steal money from him, and they begin reforming themselves for their lord Oden.

Oden keeps dancing naked in the Flower Capital and losing all the trust of the people. One day, Orochi comes to Kuri and reveals his evil plan for the Land of Wano as well as his brutalities against the country’s mobster and Oden’s friend, Hyogoro and his wife. Despairing and in a rage, Oden finally decides to take down Orochi’s supporter, Kaido.

Luffy and the rest of the Straw Hat crew are excited to see Jimbei again and welcome him as a new member. Meanwhile, Law and the Akazaya members strategize on how to enter Onigashima and attack Kaido. As the Straw Hats approach the giant torii gate in front of Onigashima, they are attacked out of the blue.

While Luffy is hurrying to the rooftop and Yamato is trying to catch up to Momonosuke to protect him, the Akazaya members finally face off against Kaido. Hearing Kaido jeering at them for being weak, the samurai retainers attack him relentlessly, remembering the day Oden told them to master his sword skill.

The formidable Lead Performers of the Animal Kingdom Pirates stand in Zoro’s way as he tries to get to the rooftop. Marco sees his late comrade in Zoro’s determination and tries to pave the way for him.

That unparalleled laugh! The Akazaya regain hope upon witnessing Oden's return. They failed in their attempt to take down Kaido, but after twenty years, they team up with Oden again to finish the job!

Realizing Onigashima’s impending threat, imperiling everyone’s life, Yamato and Momonosuke launch a secret operation. Meanwhile, Sanji and Zoro are both in a deadly battle against Queen and King.

Zoro still can’t gain control of Enma which keeps extracting his Haki. Backed into a corner by the formidable King, Zoro remembers the encounter with an old man in his hometown when he was a child.

The samurai and the Straw Hats shout for joy as they hear that Luffy defeated Kaido. Meanwhile, Momonosuke informs Zunesha of a major decision that he made. However, when Yamato calls on the Animal Kingdom Pirates to stop fighting, the earth trembles.

Vegapunk Shaka shares with Robin and the others his theory about an ancient kingdom and the 100-Year Void. He even says that he visited Ohara after its destruction. Meanwhile, Luffy and Chopper try to activate the giant robot and something surprising happens.

The Seraphim suddenly start attacking the Straw Hats and the Vegapunk Satellites. They are not stopping even when the Satellites order them to. When Luffy and Zoro are cornered, Lucci and Kaku wake up and make them a surprising offer.