Hope has not told her parents she is divorcing Jeffrey, but when he turns up during their visit, the truth comes out. Big time, as it happens, because Hope's mother then reveals to her that Hope's father is not her biological father.

A lonely Hope spends the night with a handsome stranger, but it's possible that she's in for more of a relationship than she bargained for - he may be her brother. Distraught Hope does the unforgivable: she forgets to enter Dennis in the local Emmy Award competition, which he is sure he will win after 23 years of being passed over.

The new station manager orders Hope to arrange a Growing Pains reunion show, but there's a problem - Dennis refuses to be in the same room with his rival, Alan Thicke. Meanwhile, Scott, the little boy Gloria used to baby-sit turns up, grown up and still infatuated with her.

Gloria becomes a fast friend with Louis's new girlfriend Jennifer, which leaves Hope feeling left out. Meanwhile, Dennis is obsessed with writing updates lyrics to the national anthem and performing them on his show.

The girls vie for the attention of their new neighbor and persuade Louis to find out which one he likes more. Meanwhile, Dennis and Gwillem battle for the preferred parking space of a recently deceased studio employee.

After Hope's divorce becomes final, the girls decide to be ""two gals on the go,"" and go to New York City for the weekend, where they visit the Central Perk coffeehouse.

When Hope dates a handsome, charming doctor, Gloria and Louis become convinced that he's married because he won't give her his telephone number and only sees her when no one else is around. After they prove to her that Ben is not only married but dating several other women, Hope plots revenge.

Hope and Gwillem hustle to produce the momentous 5,000th telecast of The Dennis Dupree Show, and wind up with an eye-popping pastiche, featuring clips of Dennis with the likes of Wiliam Devane and Grant Show, a trip down Memory Lane with Dennis' first piano teacher, Miss Mae, and a special appearance by the Alelgheny Women's Triple Trio. Hope lines up 500 celebrities, only to have her plans doused by a torrential rainstorm that shuts down the airport. Dr. Joyce Brothers shows up but refuses to stay and save the day. Meanwhile, Gloria hits the books with fervor as a new night school student, but six-year-old Sonny is mad at his mommy for not being home and lashes out at babysitter Hope.

Gloria suffers a crisis of nerve after she finds a note she wrote to her future self 15 years ago setting out her life's goals, all of which remain unaccomplished. To regain her equilibrium she sets out to carry through on at least two: learning to scuba dive (with a reluctant Hope in tow), and erasing a graffito about her former teacher from atop a water tank.

Hope decides she wants to be a mother after her ex, Jeffrey, announces that he and his new wife are having a baby. Her search for a father starts on the Internet, then leads to Louis. Meanwhile, Gloria portrays a ""love witch"" on The Dennis Dupree Show.