The Doctor and Sarah answer a distress call and find themselves on Zeta Minor, the last planet of the known universe, where a Morestran expedition has gone missing.

The Doctor realises that Zeta Minor lies on the boundary between the universes of matter and anti-matter and something on the planet won't let the Morestrans leave.

The Doctor makes a deal with the Anti-Matter Beast to return all the anti-matter to the planet but Sorenson is determined to continue his research.