Alice welcomes home daughter Patricia and granddaughter Nikki who have come to Cardale to get medical treatment for Nikki's leukaemia. Andrew has his work cut out with Ronnie and the community hospital whilst Joanna makes an interesting career move and it's time to say goodbye to Kim.

Despite knowing what they stand to lose David and Patricia continue their affair. Unbeknown to them Alice is aware that something is brewing between them. Meanwhile Joanna surprises everyone with her DIY skills and Andrew takes a trip out of Cardale to help out at a friend's clinic.

The Beeches staff decides to help the fight to save the community hospital. They find a true allie in Ronnie who uses his experience to their advantage. Sam continues to stand by the Sinclair's in their time of need and Andrew and Dawn try to hide their feelings for each other.

Dawn throws herself into organising a barn dance to raise money for the community hospital. Andrew and Joanna lend a hand and the evening looks set to be a big hit. Elsewhere there are complications for the Sinclair's when Alison develops a blood clot. Sam prepares them for the fact that their baby has to be delivered now. However not even Sam is prepared for the shock that lies around the corner.

Dawn is affected when a patient requests a referral for breast implants. She is unnerved when Andrew agrees with Joanna's referral and wonders how he would fell if her breast cancer were to return.

Cardale is thrown into a state of shock when Alice is brutally attacked in her own home. Can the pillar of the community recover from this devastating intrusion. Meanwhile Joanna, who is torn apart with guilt over the attack, turns to Martin for comfort.

Andrew and Dawn face a tough time when Trent becomes seriously ill, however the arrival of Trent's dad Keith signals that their problems have only just begun. Elsewhere Alice returns home and Sam takes part in the community tug of war.

Andrew returns to Cardale, six months after leaving Will and Erica in the lurch. Can he persuade them to take him back? And a bereaved husband fights for custody of his epileptic daughter

As David's family join him in Cardale, he has to give the parents of a young boy he delivered 11 years ago some shattering news. Andrew has his powers of persuasion tested by a needle-shy patient whose exotic trip of a lifetime is put in jeopardy by his fear of jabs. And baby Emily's illness continues to put Will and Kate's relationship under strain

On his way to Erica's birthday party, Andrew is involved in a car crash. Although he is seriously wounded, he battles to save the others. But will any of them survive the night? Erica is ruffled when she is called out to treat an unusual patient

David helps an old friend - now a paraplegic - and his wife to conceive. But will a baby heal the rifts in their marriage?

David helps bus driver Stan keep his job. But is Stan really as fit as he pretends? Andrew's relationship with accountant Gina Johnson goes beyond strictly business

A young girl stumbles into Cardale in search of a new start just as Andrew decides to tell Erica how he feels about her and what find out her respond.

When Emma and Tom go missing David and Claire are forced to face up to the reality of her illness - can they get past this difficult stage? Meanwhile a fire at Erica's house brings she and Andrew to a decision over their relationship.

A meningitis outbreak throws Cardale into chaos. Andrew, Erica and David work around the clock trying to avoid further cases of the disease and convince the health authority that all the children need to be vaccinated. Meanwhile Andrew and Erica discuss their relationship

Andrew arrives back in Liverpool and is meeting fierce objection from his mother over his treatment of her. Erica is involved in a highly sensitive child abuse case that splits Cardale in half. Joanne takes her authority at the surgery too far and locum Nick Goodson arrives......

Back from Liverpool Andrew is ready to look to his future with Erica but questions arise over her commitment to him. The situation is not helped by Nick's intervention. Meanwhile David is concerned when Claire's behaviour begins top spiral out of control – is she getting sick again?

The Beeches staff are slowly alerted to Nicks' web of deceit. It appears his stories and his actions have fooled them all. Back in Liverpool it's a sad day for the Attwoods when Rose passes away.

When the new doctor from The Health Centre takes a shine to Andrew, Erica realise her true feelings for him. It's time for her to bite the bullet and let him know how she feels. How will he react?

It's time to say goodbye to a much-loved regular as Laura departs for pastures new. Meanwhile Andrew and Claire's involvement with a schizophrenic patient takes a dramatic turn when she holds them both hostage. Erica and David can only wait as news filters through and a gunshot is heard........

Cardale prepares for the wedding of Andrew and Erica but a long line of disasters provides them with the perfect pre wedding initiation test. The pop band turns into a group of line dancers, the caterers pull out and the grooms suit doesn't fit, but surely the most pressing issue is the last minute doubts looming over the bride.......

Andrew and friend Ronnie are involved in a serious accident whilst rally car racing. Andrew escapes with minor injuries but Ronnie is in danger of losing his life if he doesn't receive urgent medical assistance.....Enter Dr Joanna Graham.

As Patricia prepares to leave for America David agonises over where his future lies. However the decision may be taken from his hands when he is involved in a serious accident. Will Andrew and Joanna, who are tired of his recent behaviour, be able to save him?

Claire arrives back in Cardale and announces she is selling David's share of The Beeches. As David owned the larger share, The Beeches looks set to fold unless Andrew can convince Joanna to become a full partner in the practice.......

Joanna runs into the middle of a medical emergency whilst on her day off. Rita Barratt arrives back in Cardale and back at The Beeches there's a special delivery for Dawn and Sam.

Joanna and Martin take on the sensitive case of a terminally ill teenager. Andrew and Sam go out of their way to help a couple stranded on a riverbank but things take a turn for the worse when Andrew is badly injured. Unconscious and unresponsive - is this the end for Andrew?

Andrew finally comes face to face with Keith after Dawn decides to leave Cardale - will he let her walk away? Sam is knocked sideways when Anna returns - does her future lie with him? It's new beginnings all round as Andrew, Joanna and Sam face the future without their partners.