Trying to stop an Indian uprising, Bowie only gets into more trouble after telling a native Cherokee princess the story of John Smith and Pocahontas.

Bowie goes after a thief who has trained a chimpanzee to climb up through people's windows.

Bowie is duped into helping a group that is plotting the President's assassination.

After a newspaper prints a poem about him, Bowie confronts the editor, who is later found murdered.

Bowie resolves to help an indentured servant girl from Ireland, whose unwilling services have been purchased by a mean widower.

When Bowie and his newspaper friend unwittingly help a fugitive from justice, a bounty hunter pursues them all.

As if his passport difficulties weren't enough, when Bowie crosses the border into Texas he finds out that someone is trying to kill him.

At the President's urgent request, Bowie guides a doctor to a Choctaw village to cure a sick boy, only to discover that the doctor is an inexperienced youth fresh out of medical school.

In Natchez, Bowie tries to find a new home for an infant who was the sole survivor of an Indian attack, but has trouble with the sheriff.