Buddha sends a messenger, the Boddhisattva Kuan-yin the Compassionate, to find a holy man to make the journey from China to India to fetch the large vehicle scriptures. She chooses the boy priest Hsüan Tsang, and bestows upon him the name Tripitaka. Joined by the irrepressible Monkey - with his magic wishing staff and magic powers - and a talking horse, this could be a journey to remember...

When the magistrate Lord Li's stepdaughter is kidnapped by bandits, Monkey reluctantly takes on the job of catching them. He soon learns that the bandits are not what they seem, but their bark is far worse than their bite. Meanwhile, Tripitaka, Pigsy and Sandy spend the night at an inn that's owned by a wicked dog-woman. She has a big surprise in store for Tripitaka.

Tripitaka is visited in a dream by the restless spirit of the deceased king of the land of Cockcrow. He tells Tripitaka he was murdered by a Taoist magician and thrown into a well; for the past three years this magician has been impersonating him. With the help of the king's son, Tripitaka and his disciples set out to prove that the current king is a fake.

The Prime Minister of the Kingdom of Buddha's Law invites Tripitaka and his disciples to stay as his honoured guests. He tells them of the difficulty in controlling the black magicians, shape-changers and bandits who live in the nearby mountains. Tragedy strikes when Tripitaka becomes critically ill with Tibetan Fever. Meanwhile, Pigsy leads the guards in a search for the vampire responsible for a girl's murder. He makes a shocking discovery.

To escape from a deadly blizzard in the Himalayan foothills, Monkey, Pigsy, Sandy and Tripitaka take refuge in a small cave. With Tripitaka's death from starvation looking imminent, Monkey tricks Pigsy into going out into the cold to sacrifice himself to provide food for the master. Grief-stricken Tripitaka believes he has eaten his disciple, and becomes possessed by the spirit of Pigsy.

Forty years before the pilgrims' journey to India, two lovers Chun-Ying and Yu-Lee disobey the God of Fertility Ju-Lee by eloping together - love is forbidden in his country. As punishment, he separates them and turns the young Yu-Lee into an old woman, the Keeper of the Well of Small Blessings. To regain her youth and her man, she must make Tripitaka drink the magic water. Things get very strange indeed when Pigsy and Sandy drink the water and become pregnant.

The pilgrims enter the Kingdom of Lo-Chun, the Queen of Fire, where they are prevented from continuing their journey by the active volcanoes in the Fire and Flame mountain range to the west. The Queen of Fire has a magic fan that can extinguish the fires. Ever since her husband, the Spirit of Water Buffaloes, left her for a human woman, she's lived as a recluse. So getting her to lend them her fan could be quite a challenge.

Monkey, Pigsy and Sandy become disillusioned with the pilgrimage and go their separate ways. Monkey flies home to his Kingdom of Fruit and Flowers. Pigsy goes back to China seeking rewards from the Emperor. Sandy returns to the Western Heaven, hoping the Jade Emperor will forgive him. Tripitaka continues his journey. He's flabbergasted when lightning strikes the horse and it turns into a human called Yu-Lung. Deserted by his disciples, Tripitaka soon finds himself in grave danger.

After getting separated from Pigsy and Sandy, Monkey and Tripitaka find a creepy house in the middle of nowhere. They are shown hospitality by Mr. Chin and his daughter Kohran who live there. After he befriends Kohran, Monkey discovers that there's more to her father than meets the eye. Meanwhile, Pigsy and Sandy are kidnapped by the man who murdered Mr. Chin's wife thirteen years earlier. He plans to abduct Kohran...

While having lunch, the pilgrims catch a mischievous young boy called Chou trying to steal food from them. Monkey takes him home, and falls instantly in love with his mother, Shugyoku. Chou's father was killed by the fire-breathing Tiger Demon two years earlier, but Shugyoku detests violence, and insists that Monkey should not get involved. Monkey takes a break from the journey to India, and stays with Shugyoku and Chou. Will Tripitaka and the others ever see Monkey again?

Tripitaka has an ominous dream that his mother is dying, and becomes very preoccupied the next day. Concerned about his master, Monkey cloud-flies back to China, and finds Tripitaka's mother, Wing-Chow, infected with a deadly plague. Just before dying, she tells Monkey that her son, original name Hsüan Tsang, must continue his journey to India. Monkey returns and impersonates Wing-Chow, to pretend she's alive, fearing that Tripitaka would stop his journey and return to China if he knew the truth.