The Machine identifies a school teacher who witnessed a mob hit as their next POI and Reese and Finch rush to save his life.

When Carter finally comes face-to-face with Reese, he urges her to join forces to help with their latest POI, a scrappy young woman from the wrong side of the tracks who turned her life around and became a lawyer.

When The Machine spits out five numbers, naming the Don of each of New York’s crime families, Reese and Finch suspect Elias is planning to eliminate his competition.

The team is spread thin when a husband and wife’s numbers both come up

A lethal government operative who tracks and stops terrorist threats before they occur finds herself on the run – and the new focus of Reese and Finch's attention. However, their pursuit proves to be their most formidable when they discover that her remarkable skill set equals their own.

When a virus causes the machine to malfunction, numbers are issued irregularly; the team searches for an extremely elusive tech millionaire.

The team suspects the latest number to be a potential stalker/ killer. Root plots her escape from the institution and gives her psychiatrist a big surprise.

As the POI team seeks justice for Carter’s murder, Finch realizes one of his team members may go one step too far in order to end the war with HR. Also, The Machine gives out the number for NYPD Officer Patrick Simmons, one of the crime organization’s key players.

When an unknown entity prevents The Machine from seeing the full picture of an impending catastrophic event, it sends the team five separate numbers to help them piece together the bigger picture. Meanwhile, Root’s team of hackers arrives in New York.

Finch recruits Fusco to stick close to the latest POI, a professional 'wingman', but learning how to approach women soon becomes the least of his worries. Reese must find a way to play by the rules at his new day job. The Machine sends Finch and Root on a mysterious errand.

Samaritan shows its power by erasing crime from the city for a day in an attempt to force The Machine out of hiding.

Reese and Finch must protect Harper, a street-smart grifter, when her plan to steal cash from a medical marijuana dispensary goes up in smoke.