Oliver puts Sara Lance up at the manor and soon discovers that she doesn't want to contact her family... both because she would put them in danger, and because she become a killer since the last time they saw her. Meanwhile, the League of Assassins send men to bring Sara back, alive or dead. And Oliver discovers that Laurel will be sitting second chair for his mother's trial.

A.R.G.U.S. abducts Diggle and asks him to help recover Lyla from a Russian prison. Oliver and Felicity insist on going along to help and Isabel tags along. Meanwhile, Jean Loring advises Thea that her dating Roy is hurting Moira's chance of getting an acquittal.

The Count has a new scheme to turn Starling City's residents into clients by addicting them to a new drug and then selling them Vertigo to cure it. among those stricken are Diggle and DA Donner, who collapses in the middle of presenting his case against Moira.

When a superhumanly strong thief robs a Queen Consolidated warehouse, Central City police scientist Barry Allen comes to Starling City to investigate the case. However, despite his close working relationship with Felicity, Oliver suspects that there's more to the young scientist than meets the eye. Meanwhile, Sin asks Roy to help investigate the disappearance of a friend. In the past, Oliver, Shado, and Sara try to get Slade to the submarine so they can use the serum to save his life.

After covering from a near-fatal drug overdose, Oliver begins hallucinating people from his past. Believing he's a liability, Oliver gives the information he has on Cyrus Gold to Quentin... which results in the deaths of several police officers. Meanwhile, Brother Blood captures Roy and uses him as a test subject for his new serum. In the past on the island, Ivo gives Oliver an impossible choice to make.

A bomber nicknamed Shrapnel has set his sights on Sebastian Blood, and Oliver dons his mask to protect his newfound ally. Meanwhile, Laurel investigates Sebastian's aunt who is locked up in a mental institution, and Thea learns about Roy's newfound superstrength.

When her father won't believe her accusations against Sebastian, Laurel turns to the Arrow for help. Oliver has his own doubts about Laurel, particularly when she is arrested on a charge of drug possession. Meanwhile, Roy sets out to test his new abilities but goes berserk, putting a man in the hospital.

In the present, Slade visits Oliver and makes his intentions clear. Five years earlier, Slade, Sara, and Oliver launch their assault on the Amazo, but things go wrong when Slade learns that Oliver was responsible for Shado's death.

Sara and Roy become prisoners at the Slade and the only one who is able to save them is Oliver Queen.

When Oliver and his team destroy Slade's centrifuge, he attacks them as Deathstroke to get what he needs to find a replacement. Meanwhile, Laurel ponders what to do with Slade's information, and Oliver tries to convince Thea to help him protect their finances from Isabel.