As fog begins to cover Seattle, the doctors of Grey Sloan navigate through personal complications. Meredith and Alex attempt to save Gus, while Levi talks some sense into a struggling Nico.

Jackson creates an uncomfortable situation when he invites new girlfriend, Vic, to what he thinks is Richard and Catherine’s anniversary celebration, only to discover the dinner was called for different reasons. Elsewhere, Levi brings Nico on a trip to visit an ailing family member.

It's Thanksgiving, and while Meredith faces travel complications due to the weather, Nick steps in to help in more ways than one; Richard and Bailey seek out emergency surgeries; Amelia and Link reconnect.

Bailey is on edge when an accreditation council stops by Grey Sloan to review the residency program, while Richard sets an assessment of his own for the same day. Meanwhile, Nick returns to Seattle to perform a first-of-its-kind operation with Meredith.