Grissom, Nick, and Warrick take the case of a jogger who was killed by a wild animal in the park. It gets complicated when they discover that the jogger had his liver removed after he was killed. Catherine and Sara investigate the death of a six year old girl at shady carnival.

Grissom and Catherine investigate the apparent violent death of a woman found in a sandbox. Warrick and Sara are called to a crime scene to investigate a shooting, which initially appears to have taken place during a robbery.

Grissom investigates the murders of four monks who were shot point blank while chanting in a Buddhist temple; Catherine reopens a cold case in which her best friend was murdered, after the man convicted of the crime claims he's innocent shortly before he dies.

Season Finale. The CSIs investigate when the body of an unidentified young woman is discovered stuffed in an overturned shopping cart near a freeway underpass. Her horribly disfigured and partially decomposed face is a nightmare of blood, scabs and scars, as if she'd been shoved into a fan. A huge circular hole dominates her left cheek. Someone not only wanted her dead, Grissom reasons, but ""they wanted her ugly."" Adding to the mystery are the cart's other contents: an expensive handbag, fashion magazines and a leather day planner with notes written in code.

The team is introduced to the ""Furry"" side of Vegas when a man is found dead on the side of the road, dressed in a racoon suit. Elsewhere in Vegas, a gunshot victim is found in a deep-freezer, frozen solid.

Catherine and Sara deal with the death of what at first seems to be a transvestite. Later during autopsy they find out that the make-up he seemed to be wearing was actually facepaint, he was a clown. Grissom, Nick, and Warrick deal with the death of a man in a homeless area. They found out he worked in a recovery center for drug users.

A woman who was pulled over by police is found murdered two miles up the road from the stop. It's not long before Robbins determines that the woman is, genetically speaking, not a woman.

When a major Las Vegas player is found dead, Ecklie orders both teams to investigate the case. The man who had secrets on everyone in Vegas had a very big one of his own.

The CSIs investigate the gruesome murder of Lady Heather's estranged daughter, Zoe, who was found in the middle of the Vegas desert.

In the season finale, the CSIs wait by the bedside of one of their own when he's shot in the line of duty. One CSI faces a hard choice by having the power of attorney over their injured friend and colleague. Meanwhile, the team also investigates the strange way of life of one man when he is found decapitated by a train.