Peter runs against Lois for a seat on the school board.

Quagmire takes Peter to work but Peter messes things up, causing Quagmire to lose his job as a pilot. After not being able find another job, Peter and Cleveland make plans to help him get his old job back. When the plan fails, Quagmire receives advice from his idol, Hugh Hefner.

Lois and Peter sail off on a cruise. Jealous that he was left behind, Stewie's matricidal tendencies are rekindled. When Brian challenges him to actually do it, Stewie carries out his diabolical plan.

Peter and Lois's marriage hits a bit of a snag. When Brian wins the New England Rising Writer's award, the three of them head to Martha's Vineyard for a nice relaxing vacation. Peter's usual drinking habits take over, and he soon spirals out of control, as does Brian's self restraint, as he soon professes his love for Lois. Peter and Brian test their friendship over the woman of their dreams.

After being pregnant for seven years, Bonnie finally gives birth to a beautiful baby girl named Susie! Stewie quickly falls for the little tyke and vows to do anything to win her heart and get in her diaper. Meanwhile, Joe borrows $20,000 from a bookie to pay for Bonnie's medical bills, but then plans to steal the money from Mr. Pewterschmidt to pay his debt.

When Brian discovers that his beloved Jillian is getting married, he hits the sauce to drown his sorrows. The next morning, he wakes up with more than a hangover. After realizing he has hooked up with "The Hills" star Lauren Conrad, he wants to run and hide. When Brian discovers Lauren is nothing like how she's portrayed on TV, he thinks he may have found his perfect match – if only he can let Jillian go.

After attending to the concert of a teen superstar, Stewie discovers a surprising secret about the singer. Meanwhile back at home, Chris tries to prove the existence of the Evil Monkey.

When Chris and Stewie go missing for several days, Lois is at her wit's end until she sees a psychic who assures her they are safe. Even after the boys return home, Lois and Peter's psychic obsession continues, and Peter takes it a step too far when he starts charging neighbors for his extrasensory perception. Meanwhile, Chris develops a crush on a girl at school.

Brian decides to confront Rush Limbaugh when he comes to Quahog for a book signing.

Brian and Peter are required to attend a 12-step program to deal with their drinking problems; Death gives Peter a glimpse of what life would be like without alcohol.

On the return from an adventurous day at an amusement park, the Griffins’ car breaks down in Amish country and they are stranded with no way out. When Meg falls for an Amish boy, the Griffins then find themselves in a crusade against the conservative locals.

It’s winter in Quahog, and Lois’ parents take Stewie away on a trip. But when Carter falls asleep at the wheel, the family decides it might be time for him to retire. Peter and Lois take the clan to Florida to check out some fine retirement communities, but Carter refuses to go down without a fight.

Meg's exciting European adventure comes to a halt when she is kidnapped; Stewie and Brian embark on an action-packed rescue mission..

Brian abuses Stewie's time machine and causes reality to run in reverse. So the two must work together to set things right before Stewie is “unborn.”

When the Griffins find themselves in a financial bind, Lois is forced to find a job of her own. She gets discovered by a "voiceover" talent agent named Randy, who actually runs an adult-only phone line and pays his employees generously. As Lois settles into her new gig, she hears Peter's voice on the other end of the line.

Peter is convinced that a restaurant placemat is a treasure map. Word quickly spreads about the alleged cache, sparking a city-wide search and turning the citizens of Quahog against each other.

When Peter's mother dies, he befriends her longtime pal Evelyn, who tries to seduce him. In the meantime, Stewie feels despair upon dealing with the realities of death.

Brian's cosmetic surgery leads him down a new career path as a real estate agent, which gets him into trouble with Quagmire.

When Brian takes the SATs for Meg but doesn't do very well, the family starts to doubt his intelligence; Peter tries to show Brian the upside of being stupid.

Lois books a fun couple’s vacation in the Bahamas. But, much to Peter’s surprise, it turns out to be a marriage counseling program instead. Meanwhile, Carter watches the kids at home and becomes frustrated that they’re too into their electronics to play games the old-fashioned way. So he tries to fix it himself.

Peter’s sister, Karen, decides to come for Thanksgiving and bullies Peter the same way Meg treats him. While Meg is at first amused, she later feels badly and decides to help Peter train to defeat his sister in a wrestling match. Meanwhile, to avoid overeating on Thanksgiving, Stewie and Brian decide to go on a cleanse, which Stewie takes one step too far.

To pay for Stewie’s private school, Lois becomes a postal worker. She finds a letter from Peter that was never sent to his old fling, Gretchen, dated a week before their marriage. When Gretchen tries to come between Lois and Peter, Lois has a plan of her own.

In order to "save" Stewie from autism, Peter and Lois decide not to vaccinate him and then proceed to convince the rest of Quahog to follow suit. Stewie runs away to save himself from diseases until Sean Penn swoops in to save the day and brings vaccines to the whole town.

Peter helps Joe out with several crime cases, but when Joe tries to take all the credit, Peter gets extremely angry. Meanwhile, Brian convinces Stewie to join a football team and panics when he gets a concussion.

Stewie and Brian get into a friendship-ending fight after Brian commits a terrible act to one of Stewie's beloved toys. Meanwhile, Peter refuses to wash his hand after meeting his favorite breakfast cereal mascot, Boo Berry.

The Pawtucket Brewery hires new bosses, who decide to change the company's mascot. In an attempt to be crowned the new face of Pawtucket Ale, Peter and Brian go head-to-head.

Brian worries about the legacy he's leaving behind, so Stewie makes a robot duplicate as a living biography.

When the brewery announces it will be firing one employee, Peter is nervous he will be the one let go; the family departs on a Yacht Rock cruise that doesn't go as expected.

When Meg takes Stewie to the mall to meet Santa, she has a surprising response. Meanwhile, Stewie is entirely scarred from the same experience and Brian tries to help him process it.

Peter's non-stop sweating becomes a liability at his company, so his boss tells him to work from home. Meanwhile, after Stewie and Chris cause thousands of dollars in damage to an electronics store, the two create a fake Kickstarter campaign with Brian to pay back the money.

When Joe asks Peter to be the godfather to his daughter, Peter commits to his mistaken interpretation of the role so much that he becomes a real gangster.

After feeling unappreciated by her family, Lois taps into her villainous side and attempts to win "Best Customer" at her favorite coffee shop.

Impelled by nostalgia, Peter recreates movie scenes from his favorite decade; Stewie and Doug compete to retrieve a Frisbee stuck at the top of the jungle gym.

Peter hires the town's new lawyer, Brick Baker, to represent him in litigation against his new neighbor -- who turns out to be Brick; Brian and Stewie become lobstermen and save Rupert from the perils of the deep.

Resolved to enjoy a family movie night, the Griffins take a road trip to Bend, Oregon, to rent a VHS from the last Blockbuster in existence.

Stewie and Doug compete for the honor of class “snack captain”.

After Brian's Instagram is hacked, Meg takes Stewie and Brian to Russia, only to realize she'd rather stay there. Meanwhile, Lois reverts to her tormented teenage self when Quagmire starts dating her high school bully.

Meg discovers her tears produce delicious cookies, and her, along with her siblings, enjoy a profit until the success makes her too happy to cry. Meanwhile, Peter and the guys launch a "male talk show."