Bonnie and Lois take a little trip to Paris where Bonnie crosses the line.

When Brian discovers that Carter Pewterschmidt’s pharmaceutical company is withholding the cure for cancer from the public in order to gain more profit, he and Stewie plot to expose the big secret that could change the world. Meanwhile, Quagmire reveals a hair-raising secret of his own.

Chris leaves home to move in with Herbert while Stewie and Brian become obsessed with singer Anne Murray.

Peter is convinced that a restaurant placemat is a treasure map. Word quickly spreads about the alleged cache, sparking a city-wide search and turning the citizens of Quahog against each other.

After attending obedience school, Brian becomes much more submissive, and Peter realizes he misses his old, feistier pal. Meanwhile, Chris makes a new friend at school, but feels betrayed when he discovers it was all a ploy to get closer to Meg.

Peter overloads his phone with apps. He buys a new phone with more memory, gives his old phone to Chris, and hilarity ensues. Stewie joins a tennis club and invites Brian to be his tennis partner.

The guys try to start a podcast, but Peter goes solo and branches out as a DJ. Meanwhile, back at the Griffin home, Lois' allergy forces Brian to move into Stewie's bedroom and the two have roommate difficulties.

Vladimir Putin comes to Quahog after Peter writes to him about an alternate ending to the Russian version of Rocky IV (1985).

After a mishap at work, Peter decides to take his health more seriously and diet with the help of Quagmire, Joe, and Cleveland. When Lois takes a stab at writing a romantic fantasy novel, a curious Brian and Stewie investigate to find out who she might have a crush.