WrestleMania SmackDown features a pair of colossal matches: The Andre the Giant Memorial Battle Royal and a Fatal 4-Way Match for the SmackDown Tag Team Championship.

Cesaro issues a challenge to Universal Champion Roman Reigns. Kevin Owens challenges Intercontinental Champion Apollo Crews. Tamina goes one-on-one with Nia Jax. Rey & Dominik Mysterio face Otis & Chad Gable.

Daniel Bryan puts his SmackDown career on the line as he challenges Roman Reigns for the Universal Title. Apollo Crews defends the Intercontinental Championship against Big E. SmackDown Women's Champion Bianca Belair teams with The Street Profits to face Bayley & SmackDown Tag Team Champions Robert Roode & Dolph Ziggler.

A special Throwback SmackDown sees Cesaro seek an opportunity at Roman Reigns' Universal Title at WrestleMania Backlash when he faces Seth Rollins. Questions surround Jimmy Uso's return after more than a year out of action. Bayley baits Bianca Belair into a brawl.

Natalya & Tamina challenge Shayna Baszler & Nia Jax for the WWE Women's Tag Team Championship. Cesaro sends Universal Champion Roman Reigns a message ahead of WrestleMania Backlash. Apollo Crews presents Commander Azeez with a special award.

Rey & Dominik Mysterio defend the SmackDown Tag Team Championship against Dolph Ziggler & Robert Roode. The Usos compete together for the first time in a year against The Street Profits. WWE Women's Tag Team Champions Natalya & Tamina take on The Riott Squad.

The Usos challenge Rey & Dominik Mysterio for the SmackDown Tag Team Championship. Apollo Crews defends the Intercontinental Championship against Kevin Owens. SmackDown Women's Champion Bianca Belair issues a challenge to Bayley.

Rey Mysterio seeks retribution on Universal Champion Roman Reigns. Seth Rollins joins Bayley on "Ding Dong, Hello!" Shinsuke Nakamura faces King Corbin. Kevin Owens & Big E battle Sami Zayn & Apollo Crews. Liv Morgan takes on Carmella.