A renegade Amazon, Aresia, leads a new incarnation of the Injustice Gang to accumulate the components for a bio-weapon.

Exposed as a criminal, sentenced to prison, and terminally ill due to long term kryptonite exposure, Lex Luthor escapes and assembles a supervillain team consisting of Cheetah, The Shade, Solomon Grundy, Star Sapphire, Copperhead, and Ultra-Humanite to take on the Justice League, calling themselves the Injustice Gang. The Joker also becomes part of the team, but on his own choice. However, this gang proves short-lived as its major weakness proves no match for Batman's wiles.

Exposed as a criminal, sentenced to prison, and terminally ill due to long term kryptonite exposure, Lex Luthor escapes and assembles a supervillain team consisting of Cheetah, The Shade, Solomon Grundy, Star Sapphire, Copperhead, and Ultra-Humanite to take on the Justice League, calling themselves the Injustice Gang. The Joker also becomes part of the team, but on his own choice. However, this gang proves short-lived as its major weakness proves no match for Batman's wiles.

Gorilla Grodd brings together a powerful team of villains, welding them together into a close-knit group. Meanwhile the League is plagued by it own internal problems and non-cooperation, leaving them vulnerable to attack.

The Secret Society take advantage of the League's break-up to bring them down until only Green Lantern remains to free his comrades. When he falls as well everything looks hopeless.