When a former surf champion is murdered in his home, the CSIs are determined to find the killer. Ted Henderson is killed in his own home and his body is missing, while his wife and son are left beaten and bound. While searching the home, Horatio finds heroin in the son's room and learns that he is secretly a drug dealer. Meanwhile, the CSIs find a home pregnancy kit in the bathroom that reveals Ted's wife is pregnant, but Alexx finds proof that the baby could not possibly be Ted's. Now, Horatio and the team find evidence that suggests that someone at Ted's surfboard manufacturing plant was not only the son's supplier, but may have a strong motive for the murder as well.

Horatio is quick on the scene when an armored truck carrying $3.2 million is robbed in a daring downtown heist. During the holdup, the driver is killed and Horatio guns down one of the two thieves. The other escapes with the loot, but the money turns out to be counterfeit. The team must figure out what happened to the bank's money before it was replaced with fake bills. Making the day even worse for Horatio, Yelina spies him with his niece and assumes the girl is his illegitimate child, not her own late husband's daughter.

Josh Dalton, a hot, young reporter for the Miami Sun, witnesses the murder of his friend, a city councilman's aide, in Miami's drug district, the Golden Triangle. Josh, who was suspiciously unharmed in the attack, claims that they were only down there on a story, but Horatio believes that there's more to the situation. Later, another writer from the same paper is found shot to death inside the trunk of her car, which was reported stolen. Now, as the evidence rejects Josh's version of what happened, the CSIs find themselves entangled in the world of fast-paced journalism and learn that there is a dangerously fine line between the truth and what sells newspapers.

An adult film actress is found strangled in the park and the CSIs must find the killer. Blood and human tissue are found under Ashley Anders' nails and the DNA matches that of the CEO of the company that distributes her films – and he's a registered sex offender. Also, Calleigh discovers his answering machine audiotape on which he makes a threat against Ashley. However, there is an accident back at the lab with this crucial piece of evidence and Delko was the last person to handle it. Now, IAB's Rick Stetler is put on the case, much to Horatio's dismay, as the CSIs try to uncover further evidence in order to find the girl's killer.

After a large yacht slams into a major Miami bridge, the team finds that the man steering the boat was shot and killed before the accident. The victim's wife reveals that their son had been kidnapped and her husband was handing over the ransom – three million dollars worth of jewels. But when the team learns that the jewels were fake, the investigation leads them into a dangerous situation at a jewelry shop that may contain crucial evidence, where Horatio must face the unimaginable when one of the team is killed in the line of duty.

The wife of a famous baseball player is brutally killed in her home and her philandering husband is charged with the crime. The jury on the case, as well as the accused and his defense, visits the house to examine the crime scene, but when the lights are dimmed, as they were when the victim was killed, and then turned back on, the ball player is found dead with a meat clever in his back and a note that reads "guilty." Now, as Horatio and the team find that the husband's defense team tampered with the crime scene, they must examine the evidence to find the couple's killers. Meanwhile, Horatio gets a call from Yelina, who tells him that her son, Ray, Jr., is missing.

The team investigates a modern-day piracy off the coast of Miami after six bodies are discovered floating in the ocean tied together by rope. Horatio suspects that a ship was hijacked with some of the crew killed and then dumped overboard. Evidence suggests that other crew members might have escaped on a life raft. Using radar and GPS technology, the CSIs find survivors but their stories don't match. Now, Horatio and the team must learn what really happened out in the ocean as they find themselves investigating the seamy underbelly of Miami's militias and arms dealers.

The CSIs uncover a complex counterfeiting operation after a bellboy is found murdered at one of Miami's hottest hotels. The luggage that the deceased bellboy had been loading, as well as a heist of a special paper that money is printed on, leads the CSIs to uncover a complex counterfeiting operation. It's cruise season in Miami, which means that the population of Miami swells, giving the team even more suspects to the murder. Meanwhile, Calleigh must investigate when a woman goes missing, and is later found dead, after she and her husband attend a hot and flirty "friction" party.

An extreme skateboarder and videogame tester is found dead on a half-pipe platform used to program extreme skateboarding video games. The CSIs discover that he was wearing reflective sensors when he was killed, so the motion-capture device used to produce these videogames recorded the murder as it happened, but not the murderer. Now the team delves into the highly competitive world of videogame programmers and testers to find the killer.

Horatio and the team are trying to figure out how to free an innocent young man after a harsh interrogation with Frank Tripp sends him to jail.

When evidence shows that a series of murders is linked to organized crime, Horatio and the team are instead lead to a pair of film students who have screenplay that contains the details of the crimes.

The CSI team must locate a woman who has been kidnapped and dialed a wrong number on her cell phone. To try and find the woman the team must first figure out whom the kidnapped woman was trying to call in the first place. Marisol has a difficult decision to make and Horatio helps her. Natalia is surprised when Ryan asks for Delko's permission to take her out on a date.

Calleigh is run off of the road in to a canal and causes freshly collected evidence to be compromised. The team must work to find new evidence, as most of the water-damaged evidence is unusable.

After a wealthy businessman is killed at a charity event the CSI's first suspect his wife who was hosting the event. The blood evidence is thought to belong to the wife or her two secret twin sisters but leads the investigators in another direction after the victim is not who they thought he was.