Dean wakes up in his own coffin. How did he return from the dead? What caused the hand-shaped welt on his shoulder? And what happened in the four months he spent in Hell, time he can't remember?

"I'll Kill her gentle." The angels want Anna dead, so Sam and Dean go on the run with the frightened girl, determined to discover the secret that has set the furies of Heaven on her.

Reapers take a break from work, and that means no one can die. But the escorts to the next world aren't off getting some R&R, unless you call being held hostage by a demon restful and relaxing.

Ambushed by angry hunters, Sam and Dean are shot and killed and sent to Heaven. Castiel warns Dean that Zachariah is looking for them in Heaven so they need to lay low while searching for an angel named Joshua who can help them since he talks directly to God. While searching for Joshua, the brothers run into some old friends and family members.

Michael has re-taken control of Dean as his army of monsters continues to move in on our heroes. Sam devises a plan to try and reach Dean and stop Michael before anyone else has to die.