When Doc Baker is unable to save a patient of his, he believes that he is unhappy being a doctor. He finds a new doctor for the town. Doc Baker stays on when he realizes that the new doctor really doesn't care about his patients.

Charles stays with a family while looking for some horses to buy. The children of the family asks Mr. Ingalls if he could possibly do something to keep their parents from splitting up. Thanks to Charles talking to the husband and the wife, they decide to stay together and work things out.

When Isaiah Edwards loses his will to live after a crippling logging accident, a letter to Walnut Grove from his worried wife, Grace, brings Charles and Laura back to the big woods to try to help their old friend.

Almanzo and Mr. Ingalls expand their business by delivery goods to Sleepy Eye. Both of them believe they know the quickest way to get there. They even place a bet...Whoever got to Sleepy Eye first before 1 o'clock had to cook the other family dinner. Both of them experience problems almost right from the start. Both of them end up making it there after the designated time. The husbands are forced to cook their wives dinner, but that doesn't go so well either.

The Wilders' budding marriage is put to its first major test when Almonzo, soon after recovering from an illness, is felled by a stroke.

Mr. Edwards and the residents of Walnut Grove make friends with an orangutan. But the friendship and the fun-loving primate's life may be short-lived when Nancy and Mrs. Olesen cause trouble.