As the nation remains vulnerable, Jack Bauer endures the worsening pathogen pain. The FBI deals with recent deadly developments while matters involving key players takes this day into a unexpected direction.

The nation remains vulnerable as Starkwood mastermind Jonas Hodges (guest star Jon Voight) remains at the epicenter of the mounting terrorist threat. Meanwhile, the FBI and the administration scramble to provide security and justice, and Jack Bauer questions a key suspect

With only six hours left, the clock races toward the series finale as President Allison Taylor faces impossible choices and much to the dismay of CTU, she enlists a private security firm to complete a sensitive task led by Mark Bledsoe. Meanwhile, Jack calls in a favor to his old friend Rick Vickers before he embarks upon a crucial mission of his own.

With only five hours left, the clock races toward the climactic series finale as Jack stops at absolutely nothing to avenge the emotional setback of losing his beloved partner Renee Walker. Meanwhile, the administration attempts to keep the historic and pivotal peace agreement on track as undermining forces surface.