Saiga and Kagura make their way beyond Tokyo's city limits, desperate to leave the dangers of their ordeal behind them. They visit Saiga's old friend, Doctor Ryogoku, hoping he can find a medical explanation for these strange Euphoric powers. And as Saiga gets lost in disturbing memories of war, the doctor makes a startling diagnosis!

When health fails, everyone is in search of answers... and a cure. As Saiga is left with a most difficult dilemma, an unexpected house call from the demented Dentist is the last thing he needs. The photographer will have to perfect his shooting skills to pass this sadistic drill.

Saiga and Kagura hit the road, with Ginza and Tsujido each tracking them using their own unique talents. Making a detour at a remote spa, Kagura learns some shocking truths about her own origins. But the most startling revelation is a glimpse into the human side of Shinsen. What secrets is the powerful woman hiding, and how will the past play out into their future?

With the latest assassin on the loose, Saiga convinces Ginza to drive him from his hiding place to see Dr. Ryogoku. The samples from Saiga and Kagura have been analyzed and an eccentric DNA specialist sheds new light on the Euphoria Syndrome. Meanwhile, Suitengu continues his plan to seize control -- by marrying Kagura instead.

As the Tennouzu Group gets rich off of their new product line, Saiga and Kagura set sail for a fresh start in a new land. But before they can vanish in the wind, they're dragged back to Tokyo by a powerful new ally. Everyone's working their own angle... but are they all working towards the same goal?

Allied with Representative Ochiai, Saiga agrees to testify at the Parliamentary hearing if his conditions are met. Kagura must be flown out of the country to safety and there get the treatment that could save her life. After a chance meeting at a bar with a young idealist named Joe, Saiga questions the selfishness of his motives and resolves to bring down Suitengu himself.

Betrayal is in the air. As Saiga fights for his life against a ruthless Euphoric posing as a friend, Kagura is attacked by the one who was supposed to cure her. Meanwhile, on a stage littered with corpses, Ginza discovers the blood-stained roll call of Suitengu's club members, finding a shocking name on the list.

On the eve of the Club's grand reopening all hell breaks loose. A sick killer with a depraved fetish holds Ginza captive. Prime Minister Kamiya reveals his plans - and his true face -- to Kagura, as war breaks out in the skyscrapers of Tokyo between two powerful Euphorics.

As Suitengu continues his assault on the Prime Minister's mansion, Saiga races to Kagura's aid. Loyalties are tested and not everyone rises to the occasion. And old wounds refuse to heal when, many years after Kamiya killed his parents and took his sister away, Suitengu finally exacts his bloody revenge.

Saiga emerges from the Prime Minister's house to find Tokyo in chaos. With all the country's leaders locked away deep within the secret club, Japan is without a government. Intent on destroying Suitengu and claiming the spoils, outside forces step into the vacuum and invade. Can Saiga, on the verge of blindness, save Kagura from what Suitengu deems her destiny?

With Ginza locked in a gun-blazing battle against Tsujido and Makabe, and as foreign missiles threaten to destroy the building at any moment, the final showdown between Suitengu and Saiga reaches its bloody climax. If Suitengu executes his plan, the streets of Tokyo will be paved with fire and the global economy will be forever changed.