Dom is killed in a helicopter accident that also severely injures String. Dom's niece, Jo, inherits and takes charge of Santini Air. The Company sends Locke to regain possession of Airwolf, he recruits Major Mike Rivers ,an Air Force pilot to help him find and fly the craft. Together they rescue St. John from a jungle prison and he and Jo round out the new Airwolf team.

The grandfather of one of four juvenile delinquents Jo and Mike have taken camping plans on killing the rest of the camping party in order to regain custody of his grandson.

The Russians reluctantly agree to allow the Airwolf team help them contain a nuclear power plant that has had a meltdown.

The Airwolf team is assigned to guard the daughter of an Interpol agent who is marked for death by terrorists.

A Japanese Kamikaze pilot who survived being shot down by St. John's father during WWII plans on restoring his honor by killing St. John and destroying a nuclear power plant.

A jet manufacturer sabotages his own plane that St. John is test piloting rather than let St. John reveal its inferior construction.

The Airwolf team is sent in to stop a group that has taken control of ten Soviet and ten American nuclear missile silos and threatens to set them off unless everyone agrees to total nuclear disarmament.

Mike and the wife of an East German double agent! pilot he had been impersonating are kidnapped at an air show in Paris.

A banana republic dictator takes St. John and the family of one of St. John's friends- who had discovered that the dictator was skimming American aid- hostage on a remote island.

Locke's girlfriend is given a behavior implant module which forces her to turn Locke over to a lady scientist who uses the same procedure on Locke in order to gain control of Airwolf.

The Airwolf team is sent to stop a man who has hijacked a Japanese freighter carrying nuclear waste. The man plans to blackmail the nations of the Earth into guaranteeing all diseased persons.

The Airwolf team travels around the world as they put an opium ring run by St. John's former commander out of business.

John comes to the aid of an old flame whose husband was killed by drug dealers.