Miss Fowl swallows a seed from Jimmy's DNA-accelerated spinach plant turning her into a 50-foot plant.

A strange meteor lands in Retroville, bearing a mysterious message in an alien language. When Jimmy is finally able to translate and answer the riddle, he, Cindy, Libby, Sheen, Carl, Bolbi, and Goddard are sucked into space - only to find that the message is an invitation to Intergalactic Showdown! Team Earth must learn to work together to win - or lose their home planet!

After a run in with a radiation belt in outer space, Jimmy, Cindy, Carl, Sheen and Libby are all endowed with super powers.

The evil Jimmy clone is back, and he's reconfigured the cloning device to make an evil clone of the Earth with an alarming side effect – the real Earth is starting to disappear.