John Chambers writes an advice to the lovelorn column under the pseudonymn Uncle George. He learns that his wife is cheating on him when a neighbor named Mrs. Weatherby, not knowing that John and Uncle George are the same person, writes a letter to his column asking for advice. Chambers kills his wife and then pins the blame on her lover. When he fakes shock when the police reveal his wife's affair, he is accepted as innocent because he doesn't have a motive. Chambers almost gets away with murder until Mrs. Weatherby tells the police that she mailed the Uncle George column asking for advice about the situation.

When policeman Philip Reardon is killed in drug bust, his police officer father feels responsible because his son joined the police force to follow in his father's footsteps. In order to set things right, Philip's father strives to brings his son's killers and their mob boss Herbie Lane to justice. The plan leads to his own death at the hands of the criminals, but in death he is able to fulfill his goal. Before the murder he had stationed a fellow officer nearby to witness the killing and bring the entire gang to justice.

Brown is a chronic gambler and bigamist who starts to run out of money when his wealthy wives start turning up dead. The police suspect that he is responsible for murder, but when no evidence turns up they are forced to conclude that each death was a suicide. The real murderer is one of Brown's wives who jealously wants to keep her husband all to herself. She tells him that if he strays again she will commit suicide and she will arrange for him to be charged for her murder and the murders of his other wives.

After being the repeated victim of harassing phone calls, Helen Clarvoe asks a lawyer Paul Blackshear to investigate a woman named Dorothy Johnson who may be behind the calls. Dorothy blames Helen for the break-up of her wedding engagement. Paul investigates and finds the unexpected.

Gerald and Milly Musgrove successfully steal $100,000 dollars, but run into the problem of where to hide the money. The couple befriend an elderly and somewhat senile woman named Emmy Rice. After a visit to her home, Gerald stashes the money in a stack of old magazines. Later, he convinces the old woman to name him in her will.

Bessie Carnby and her daughter Camilla have been feuding with their neighbors Henry and Samantha Wilkins. In order to patch things up Bessie invites them over for dinner. Samantha refuses to go, but Henry goes and tries to act friendly. Later, he disappears and Bessie sees Samantha digging a hole in her barn. Bessie accuses Samantha of murder and calls the police. The police dig up the hole and find a badly decomposing body. Samantha is executed for the crime, but later Henry returns claiming he went out to sea. He has inherited his wife's money and marries Camilla. Bessie realizes she has been tricked and, feeling guilty over having sent an innocent Samantha to her death, decides to bring Henry to justice by poisoning herself and making it look like he is responsible.

While George is headed to see his girlfriend, he meets a mysterious limping stranger who makes George fear for his life. George learns that the stranger is his girlfriend's jealous husband and that his girlfriend arranged this meeting between them in hopes that her husband would kill George. The stranger tells George that she has done this sort of thing before and that he tried, but failed, to kill his wife's last lover. The stranger convinces George to plot revenge and tells him to tamper with the steering of his wife's car. George does as the stranger suggests and his girlfriend dies. George discovers to his dismay, however, that the limping stranger was really his girlfriend's former lover and that he used George to get his revenge on her.

Eva is the wife of a miserly businessman named Henry. Eva, who has been cheating on Henry, is tricked into planning a murder him by a mysterious stranger named George who gets into their house by pretending to be a gas man. The two plan the perfect crime, until the last possible moment when George decides to murder Eva and makes it look like her husband is responsible. George is really Colin the long lost brother of Henry. He framed his brother because, years ago, Henry wouldn't loan him money for his wife's expensive surgery. She died and he has been waiting for his revenge ever since.

Glendon Baker is an invalid who is being taken care of by a nurse named Stella Crosson. Stella is pleased when another nurse named Betty Ames arrives to assist her in the work. The only other people in the house are a house keeper named Maude and her handyman husband Sam. Stella becomes worried when she hears that a nurse killer is in the area. She grows more uneasy when the lights go out. When a patient's oxygen begins to run low, Stella sends the handyman out to get some. Growing paranoid, Stella locks all the windows in the house but neglects to lock the one in the basement. Later, Stella sees a man outside and panics when there is knocking at the door. She fails to notice that it is the handyman trying to get back in. She heads for the phone, but stops and heads into the lounge to help Nurse Ames who has been apparently attacked. Once in the lounge, however, Nurse Ames attacks her.

Martha Hunter is a mail order bride who has just moved into the rundown and not well-heated home of her new husband Luke. Martha is Luke's second wife and she becomes worried when she discovers that Luke's previous wife, who was also a mail order bride, died under mysterious circumstances on a vacation to Luke's relatives. Martha grows more fearful when she finds a offin like box and sees her husband digging in the cellar. When Luke suggests that they go one vacation she grows even more nervous. Prior to their departure, Luke insists that Martha go down to the cellar. Martha becomes terrified. She pulls a gun and kills Luke. After he is dead, she takes a look into the cellar and discovers that her husband installed a new furnace as a belated wedding gift.