After performing an autopsy on a young woman Quincy finds out about a man called' Uncle Harry'. He preys on young girls, runaways, who arrive in Los Angeles alone and scared. Quincy helps Carol Treager, who runs a home for runaways whose lease is about to run out, to not only track down a missing young girl who was seen in the company of ‘Uncle Harry' but to also try and get a new place for her and ‘her' kids.

‘R.W. Collins', a famous hijacker who escaped by parachuting out of a plane with his money five years ago is found dead, hanging from a tree in the National Park he bailed out over. He died before he hit the ground and has been hanging there, undiscovered, for 5 years now. Quincy and Sam are sent to the scene to see if they can find out whom the man really was. When they reach the park they find that things are a lot worse than they could have imagined, the anthrax particles he used to hijack the plane were released when the body was found and are spreading throughout the area infecting people who come into contact with it.

After Quincy's traces an old man's death to his son's physical abuse he is faced with a similar case involving the exploitation of two elderly women by their unscrupulous nephew.

Dr. Asten's niece is involved in a car accident while drunk and it is up to Quincy to try and establish whether she was the driver of the car or whether it was her friend, who died in the crash, who was driving. Asten gets Quincy to swap jobs with him for a day so that he can find out how hard it is to run the place.

Two days after winning a boxing championship a young boxer collapses and dies while looking at new cars. At the same time Danny's chef, Alfredo, goes to a cheap doctor for a hernia operation. A routine procedure but he dies during it. Quincy's investigations lead to a connection between the two. Frustrated with Quincy never being around when he needs him Asten supplies him with a pager. That way he can contact Quincy whenever he wants, much to the annoyance of Quincy.

Three deaths due to food poisoning are linked to a football stadium where a big championship game is due to take place. Quincy has three days to find the source before 90,000 spectators come to watch and are put in jeopardy.

A father finds his son dead, having taken a drug overdose. Knowing this will affect his wife he decides to report it as an accidental drowning. Quincy's friend Volmer is the local coroner and politics lead to him not being able to autopsy the boy. He asks Quincy to help him out.

If that was not enough he also has to deal with a textile mill boss who refuses to fix irregularities at work and when an accident happens wants to hide the truth.

Quincy is hired as a technical director for a movie that is recreating a famous homicide case. Watching the murder scene being filmed convinces him that the real murderer is still loose and that the woman in jail for the crime was innocent. He sets out to find the truth but is hampered by the reluctance of the woman convicted to get involved. She only has a few months now until her parole hearing and if she is still trying to prove her innocence she has no chance of getting out if Quincy fails to find the real killer.

A young boy, Jeffrey, dies when he falls from a building, after being chased in there. After the autopsy a doctor turns up wanting to have the brain. Jeffrey had Tourette's Syndrome and the doctor wants to try and find out what causes it and how to cure it. This is the only way he can research it as the drug companies don't think they could make enough money to make it worth their while.

Sam and Quincy are attending a job fair for students when a woman falls down an escalator, just after shouting at someone who has been following her. While she is in hospital it is discovered she has a severe case of posttraumatic amnesia. A high price assassin is caught in her hospital room not long afterwards and leads to even more interest in who she is and why someone would want her dead.

Quincy and Janet finally get some time off and go on a weeks cruise. They are looking forward to some rest and relaxation together.

Before long their holiday is interrupted. Quincy is visited, late one night, by the captain. One of his crew has been murdered and he would like Quincy's advice. The murderer is caught but he has died before the morning and an autopsy reveals that he could have died from an infectious disease. A disease that could already be spreading throughout the ship!

With the cruise ship being prevented from docking at any of the islands in the area it is down to Quincy and Janet to find out exactly what the disease on board is before everyone on the ship finds out and starts panicking.

After a teenager dies from taking a seemingly harmless pill, Quincy sets out to shut down the highly dangerous, but legal, trade in ‘look-alike' drugs. He tries to find out why it is legal to make such pills and concentrates on closing down a small, local shop that sells the pills.

An old man at a hospital for respiratory disorders drops dead after going for a walk during a smog alert. Quincy's autopsy reveals lungs that had some kind of inflammation, caused by the pollutants being pumped into the air by the oil refineries near the sanatorium. Refineries that are meant to cut back their emissions during a smog alert!

A man who was a prisoner in the Nazi concentration camps is run down and killed after he recognizes the man who was his tormentor in the camp. He manages to get a message sent to his friend, Heime, before his death and he tries to convince Quincy that it was murder, not an accident. At the same time Heime, who runs a Holocaust museum, has to deal with a rich, powerful man who spends his time proclaiming that the Holocaust never happened.

Quincy is going to be testifying in the appeal of a big mob boss, Victor Ramsay, and his evidence is vital to him staying in prison. Ramsay and his people have other ideas though and have a plan to guarantee his release. They kill the only witness and then set about making sure that Quincy is discredited. Once this is done Quincy and the D.A. have three weeks to come up with more evidence or Victor Ramsay will be released.

A fraternity ‘hazing' stunt goes badly wrong and a young man, Cary Stadler, dies. The other students panic and cover up how he died by placing his body in another place. Seeing as Quincy is the ME who deals with the case their attempt is very quickly uncovered. He proves that the story they are telling the police is complete fabrication. Proving they were involved and proving exactly what happened are two completely different things though, and there seems to be nothing that the police can arrest the boys for.

When a young mother suffers from a nerve disease, Quincy fights the drug companies and the government to get her the medication she needs.

Emily comes to see Quincy about a young 18 year-old boy he has just completed an autopsy on. He died while slamdancing at a punk rock club, killed while dancing to lyrics about death, lack of hope and violence. She had been counseling his girlfriend Abby and is worried about her. Quincy's report declares that the punk music Zack listened to was a part of the cause of his death but the main reason was an ice pick in his back. Punk music and its lyrics come under the spotlight as Quincy tries to find evidence to prove who killed Zack.

A young boy, Tim, goes to do some welding at his workplace and ends up dying in an explosion. One of Asten's top field investigators, Arnold Chatham, thinks that it should not have happened. He discovers that Tim couldn't read and continues his investigation while Quincy tries to find out how someone who couldn't read managed to get through school.

An old lady is shot and killed by a burglar in her own home. When he arrives Quincy recognizes her as being one half of a couple of entertainers he saw in his youth. He remembers reading about their brilliance and wonders what happened to her old partner, Morris Perlmutter. He tries to find as much evidence as he can and then decides that he is going to find Morris. Meanwhile Morris is trying to get his big break in TV with the part of an old man in a play that is going to be broadcast live.