The surviving members of Tony's mafia plan revenge against Inferno by planning to release crucial information on certain mobsters who are suspecting of supporting Inferno from behind the scenes to discredit them and be eliminated from the inside. However, Inferno plans to conduct an assassination spree on all anti-Inferno mafia personalities in the West Coast of the United States with Ein and Zwei being in the forefront working with Lizzie to carry out the assassinations on the orders of its top leaders under insistence from Claudia. Thanks to their efforts, Inferno was able to consolidate their influence in the area.

Reiji kills Inferno's men who bombed his apartment and makes his escape. Scythe Master and Shiga explain the whole situation to McGuire, pinning the betrayal on Claudia and Phantom. Claudia calls Reiji to tell him the reason of her betrayal and needs his help to escape. Elen goes to kill Reiji per Scythe's orders and Scythe reveals the next generation of assassins he's creating: the Zahlen Schwestern and reveals that Elen is no longer needed. Claudia and Lizzie meet up and drive to the beach, where Lizzie is forced to execute Claudia for her betrayal. Reiji returns to the desert warehouse and Elen arrives to kill him. After he persuades Elen to stop, the girl wants him to end her suffering. Reiji refuses to kill her and since he has a promise he is able to keep he would like to keep it. Elen decides to leave Scythe Master and Inferno and escape with Reiji. Lizzie visits Claudia and her brother Romero's graves. After getting fake Mexican passports, Reiji and Elen prepare to leave America.

Mio's mother finally tells her the truth about her heritage and her father being alive, explaining that their separation was the only way to preserve happy memories together. Mio, realizing she feels this way about Reiji, calls to tell him about the duel between Cal and Elen and also says she will wait for him to return once he is happy. Cal arrives at the church to find Reiji there for the duel instead of Elen. Outside, Shiga and his men arrive to kill Elen, Reiji and Cal but are stopped and killed by Elen so they cannot interrupt the duel. Inside, the music ends and Reiji wins the duel, lethally wounding Cal. Crying, Reiji holds Cal as she dies and she finally releases her hatred and tells Reiji she is happy to be with him as she dies, since knowing and loving him were enough to give her life meaning. After Cal and Shiga's men are all dead, Scythe Master appears out of the shadows to begin the "finale of the play" he has written and releases the Zahlen Schwestern to kill Ein and Zwei.