Fourteen year old Miaka Yukiâ's life centred on two things- passing her high school entrance exams, and getting to eat all of her favourite dishes! But when Miaka accompanies her friend Yui to the National Library, her whole life is turned upside down when she finds herself drawn to the Restricted Section, and to a mysterious book entitled The Universe of the Four Godsâ. And, as Miaka and Yuki begin to read the story, they find themselves transported into the world of the book, a magical and mysterious land based on ancient China!

The Imperial concubine Nuriko has been revealed to be the third seishi, but as Miaka soon discovers, helping the Priestess of Suzaku is the last thing on Nuriko's mind! As Nuriko continues her campaign to monopolise Tamahome and make Miaka's life hell, Miaka nonetheless decides that she must make friends with the concubine, no matter what it takes. But will even Miaka's open and honest nature be able to win over the selfish and scheming Nuriko?

Miaka and the three seishi have made it Mount Taikyoku, but the incident with Miaka’s duplicate has left all except Nuriko drained and weak. With Miaka suffering from severe blood loss, Taiitsukun uses her magic to transfuse blood from willing volunteers Hotohori and Tamahome. Her strength renewed, Miaka is ready to be sent home, but will even the combined power of the three seishi, and the strength of her friendship with Yui be enough to pull her back to the real world?

After agreeing to be led to the bandit leader, Miaka realizes the Eiken, the "Leader", is a fat, drunken, slob! Meanwhile, Hotohori worries about Miaka and finally decides to take action. After saving Miaka, a man named Genrou abducts Miaka...

Miaka, determined to show the letter to Tamahome waits at the tree, keeping her promise. Meanwhile, Nakago catches Chichiri, who went to look for Tamahome for Miaka. It doesn't take long for everyone to realize where Miaka ran off to, including Tamahome who meets Miaka there. Will Tamahome revert back to his old money loving self?...Goodbye.

Tamahome goes to his village, but once there, he finds a terrible fate that has befallen on his family. Suboshi, who swore revenge for the death of his twin brother, Amiboshi, is in battle with Tamahome. Another member of the Seriyu Seven comes into play.

Nuriko has finally realized he loves the lady Miaka. Fearing for Miaka and Tamahome's relationship, he went to the top of Mount Koku by himself in search of the Shinzaho. Standing before the door guarding the Shinzaho Nuriko is confronted by Ashi-tare, who is a member of the Seiryu seven, and their battle for the Shinzaho begins.

Keisuke and Tetsuya finally arrive in Morioka. Miaka asks Tamahome to meet her in the tower that Xing told her the legend about. Tokaki reminds Tamahome that he and Miaka will be split up when Suzaku is summoned. While waiting at the tower, Miaka sees Yui and Nakago. After checking the police station and library, a taxi driver introduces Keisuke and Tetsuya to a friend with old newspapers on microfilm. They find the article regarding the Okuda murder and where it took place. Tamahome goes to the tower and finds Miaka’s hair tie. The rest of the Suzaku Seven join him, and Tasuki fries a monster about to eat him. Tokaki and his wife, Subaru, tell them that Tatara, the guardian of the Shinzaho of Byakko has been taken. Nakago finds Miaka sneaking into where he and Yui are staying. Miboshi, one of the Seiryu Seven, steals Miaka’s voice and Nakago knocks her unconscious. The Suzaku Seven follow Miaka. Keisuke and Testuya arrive at the location where the Okuda murder took place and find it is called Genbu Grotto. Miaka wakes up in a cell with Tatara and Yui enters.

Yui has been devoured by Seiryuu and it seems that Nakago's wish was granted to become a Deity. Miaka begins the summoning chant to Suzaku. Yui's final wish was to allow Miaka to be able to summon Suzaku! Miaka merges with Suzakuseikun for her wishes to finally be granted...

Tamahome and Nakago engage in their final battle. Even with all of his powers restored with the summoning of Suzaku, Tamahome is still considerably weaker than his adversary, and Miaka and her Celestial Warriors work to channel all of their powers to him. This plan is still insufficient to defeat Nakago, and as a last resort, Miaka decides to seal Seiryuu away using Suzaku's powers. Nakago loses all of his powers, and as Tamahome delivers his final blow, he glimpses Nakago's bitter past, his ascent to power, and his plight for revenge. The Suzaku Seven's final enemy falls at last, and they urge Miaka to use her final wish to ensure that she and Tamahome could stay together. However, her wish is to restore her world's peace and serenity, and Tamahome consents. Her mission fulfilled, Miaka and her Warriors say a tearful good-bye, and she shares a final kiss with Tamahome as the two worlds are separated and Miaka changed for the better. Days pass, and she discovers a letter which Tamahome had left for her. She learns of his promise to love her through all time and space, and his wish to find her again. Miaka and Yui eventually pass their high school entrance exams, and one school day, Keisuke leads them to a young man who is revealed to be Tamahome, still wearing his wedding ring. The story ends as Miaka lapses into tears of joy.