Captain Black hires Jackie Chan to a secret government agency - Section 13, to track down the artifacts pursued by the Dark Hand, a crime organization far darker than anyone could have known. Also, Jackie's 11-year-old niece came to visit from Hong Kong and finds herself willing to help in the fight against evil. Jackie must gather up all 12 magical talismans that the Dark Hand had started retrieving before the Dark Hand does.

Jackie and Jade have different goals after learning the Dark Hand members have stolen an endangered tortoise, which has the Rabbit talisman of super speed encrusted on its shell. And now, the Dark Hand must try to get it out, and Jackie must obtain the talisman and the tortoise before it becomes someone's dinner.

Jackie is poisoned by the Dark Hand and will give him the antidote for the talismans. Jade steals all the talismans, while the Dark Hand destroys the antidote. When Jackie fully turns to stone, the Horse Talisman heals him.

The Tiger Talisman splits the dark and light sides of Jackie in two, which makes it easy for Valmont to trick his dark side into working for the Dark Hand. The light Jackie could not do anything, he does not want to fight, while the dark Jackie steals the 12 talismans from Section 13. Both halves fight for the talisman, but Valmont gets to it first and uses it to turn Shendu into it's old self again, an alive, giant dragon demon.

Jackie and Uncle try to study the marking on the statue of Lo Pei, the warrior who scattered the Talismans, hoping to find clues to the remaining ones. When Jade shatters the statue, she finds a way to repair the damage, and brings the ancient warrior to life.