After Jamie Hoskins falsely accuses two classmates of rape after a consensual act then hits nine pedestrians during an attempted suicide, medical tests reveal she has been taking medication for bipolar disorder and stopped her pills a week earlier. Jamie is charged with murder and released on her own recognizance after she agrees to take her medication, but after rock star Derek Lord, who is well known for his negative views on psychiatry, gets involved and begins spearheading her defense, Jamie again stops taking her medication. Novak is sympathetic to Jamie, but Jamie's insistence on following Derek Lord's advice leaves Novak with no choice but to take the case to trial.

When the paternity of a missing young boy is placed into question, Stabler wonders if he really is the father of Kathy's child. Later, Stabler faces the possibility of losing not only his partner but also Kathy and the baby when she and Benson are in an accident.