In this intro to the series, Dr. Jack Morrison treats a young girl with dysentary; Dr. Annie Cavanero searches for a missing patient -- who happens to be a large, permanent resident of a local mental institution; Dr. Ben Samuels tries to recall all of his conquests after being diagnosed with VD; Dr. Daniel Auschlander's liver cancer is revealed; a bombing victim is brought into the ER, as is the young man who set off the bomb; and Dr. Wayne Fiscus and Dr. Cathy Martin begin a relationship.

Dr. Westphall risks his job by creating an isolation floor to stem the spread of the suspected Legionnaire's Disease (and the PR fiasco causes administrator Cummings to fall on his sword to save the hospital); Dr. Beale learns that Tweety got pregnant while in the hospital; Fiscus is assaulted in the E.R.; and Dr. Craig decides to sell his car.

The search continues for the source of the Legionnaire's Disease; Cavanero befriends a young woman facing a hysterectomy; Tweety makes a decision about her future; and Ellen Craig deals with the elusive Dr. Barnum.

Morrison regrets making a couple of house calls for an insistent old man; Fiscus has another run-in with a gang member; Ralph takes up eating garbage; White's daughter eats some mothballs; and Dr. Craig bawls Ehrlich out for spraining his little finger.

Ralph masquerades as a doctor; an obese woman gives birth unexpectedly; an old friend of Dr. Samuels joins the staff; and Ehrlich faints during surgery.

Dr. Samuels breaks up a late night poker game to perform emergency surgery on a gunshot victim; Morrison lets a Chinese couple perform a folk healing ritual on their dying son; and Ralph's manic stage reaches a crescendo.

Dr. Fiscus is shot. Afterwards, he experiences the afterlife and meets some old friends. Such people include old patients who died in the hospital, a few in limbo and a couple in heaven. However, he is condemed to hades and finds Dr. White swiming in circles for all eternity in a boat with only one oar.

Meamwhile, the docs at St. Eligus try their hardest to keep Fiscus alive.