Brannon Braga speaks to the quality of the cast and how human the characters they portrayed were. Matt Winston echoed the sense of family on the set and especially Scott Bakula. Scott Bakula and Linda Park speak to acting in TV series roles and how the writers take what they see in future scripts. Dominic Keating, John Billingsley, Conner Trinneer, and Anthony Montgomery talk about what interactions they had with the producers and the cast and crew members. Jeffrey Combs and Chris Black praise Scott Bakula's setting the appropriate tone on set.

Jolene Blalock begins this discussion and says she was burnt out by the third season, but still found the work stimulating. John Billingsley, Anthony Montgomery & Dominic Keating continue the discussion of the change in direction during Season Three and the lack of support from UPN at the time. Conner Trinneer discusses how 9/11 affected him and Phyllis Strong believes it had an impact on his third season performance. John Billingsley laments about the changes in Archer's character during the season while finding many of episodes to be exceptional. Linda Park talks about the advantages of serialized storytelling and that allows characters to grow and change. David A. Goodman agrees and compares the season to the Dominion War during Deep Space Nine. John Billingsley also agrees but also notes that "standalone" episodes were done to allow alternatives to be possible. Manny Coto talks about his episode "Similtude" and how it stood alone, but supported the arc.

Larry Nemecek notes that Enterprise had to get good ratings. He notes that the episodes where good, but the ratings were not that good. Judith & Garfield Reeves-Stevens mused about the signs that the show was ending. Mike Sussman noted that the budget for season four had been reduced. He notes that was mitigated by amortizing the cost across multipart episodes. This gave rise to three episodes on Vulcan, three about the Augments, three about the Andorians & the Romulans, two about the mirror universe and the final arc about the xenophobic movement on Earth at the time the precursor to the Federation was being negotiated. Manny Coto talks about a potential of William Shatner being on Enterprise via something involving the Mirror Universe. Mike and Denise Okuda noted how wonderful the original series sets (reproduced for the Mirror Universe two-parter) are. Manny Coto notes that he wanted to do more Gorns and Tholians. Several cast members comment on season four.

The effect of UPN on the end of Enterprise. Several cast members and crew comment on the "let down" that comes with the end of the show. Jolene Blalock comments on the last episode and her disappointment with it. Conner Trinneer was happy with it. Manny Coto muses about what he would have liked to explored.