An 8-year old's slumber party becomes a crime scene. Callie accepts Manus' offer and joins the FDLE as a forensic nurse. Jim's investigation into the death of a Navy recruiter leads to the ex-wife's boyfriend and her missing baby

In the thrilling season finale, Callie's hospital is on lockdown when a pair of ex-con brothers take hostages. Longworth and Callie work together to ensure the safety of the hostages, but things take a turn for the worst leaving Longworth to defuse the situation before it explodes.

The murder of a woman who contacted the Innocence Project to exonerate a death row inmate now forces Jim to team up with the detective who investigated the original case: Jim's former partner when the Florida State Attorney General's office calls her to testify against the IRS agent who handled her audit and tried to extort her for sex a few years back. Reluctant to take time off to help the State Attorney, Callie is surprised when Miranda is not only supportive of her request, but also learns that Miranda has been the victim of sexual harassment herself, and the two women bond through their shared experience.

When a man is killed by a Civil War reenactor's sword, Jim must enter the fray to find which imaginary soldier committed a very real murder. Meanwhile Callie makes a tragic discovery at work, while Jim receives foreboding news for Callie and Jeff.