Cow, Chicken, Mom, and Dad go on a safari in Africa, where they run out of gas. Cow and Chicken then find themselves at the mercy of laughing hyenas, and man-eating giraffes. Super Cow comes to the rescue, only to find that she has actually been defeated by the Grizzly Beaver, who has eaten the giraffe, who has eaten Chicken.

Teacher is disappointed when the school's plastic surgery team has no championships, so she calls in The Red Guy, to be the new plastic surgery coach. Chicken and Cow immediately join the team, and are taken to the finals, where they must compete against real doctors, who are still in grade school.

Cow and Chicken mess with a Junior Chemistry Set, and created perpetual energy, a beam of energy that keeps on going forever. The Red Guy kidnaps Cow and Chicken to recreate the energy, so he can win a trip to up North without having to sell Military Scout Cookies.

I Am Weasel: ""My Friend, the Smart Banana''

Chicken rushes through breakfast, and accidentally eats a box full of coffee flakes. He then goes crazy and has trouble getting to sleep. On his third night of no sleep, Chicken then runs up the Empire State Building. Super Cow shoots him with warm milk, and Chicken finally falls asleep.

Cow has a crush on Crag, the smartest kid in school, but is ignored by him. Her friends try to convince her that her horns are too small, so she tries every way to make them bigger by decorating them with coat hangers, paper masche, and even chocolate chip weenies. Cow later learns that Crag wasn't interest in Cow, because he had a crush on one of her friends.

Cow tags along with Chicken, Flem, and Earl on their camping trip in the tree fort. Cow says that if Chicken, Flem, or Earl touch her dream catcher that they'll die. Chicken accidentally breaks her dream catcher, and soon, he, Flem and Earl are at the mercy of Cow's worst nightmare: The Milkman.

Grandma pays at visit to Cow and Chicken's house to take them to the mall with her. Her purpose for being at the mall: to look for a new grandpa, because she lost the old one. Chicken gives her the slip while he, Flem and Earl hang out at the concession stands.

Flem and Earl find themselves lost in the middle of an ocean near the equator. They fear their lives are short, and begin reminescing about their fun lives: home coming, water boys, mentally challenged, eating cheese in Yurp, running with the bulls in Pimplelotta, singing drinking songs in Germany, and having love for Cow.

I am Weasel: ""I.R. Do""

Sick of their everyday life of being squirted with milk, Cow's favorite toys: Crabs the Warthog Doll, Piles the Beaver Doll, and Manure the Bear decide to run away to find their original owner. After reading Manure's tag that says ""Made In Hong Kong"", they assume their original owner is a maiden named Hong Kong, and set out on a quest to find her.

Cow and Chicken wait outside the hardware store while Dad shops. Chicken is dying to ride the fighter jet plane ride. When Cow finally lends Chicken a quarter, The Red Guy takes the ride away. Chicken then stows-away on his truck, to ride the plane, but has to plug it up. Once at the gas station, he buys 20 extension cords, but the owner unplugs them. In the end, Chicken discovers that Dad actually collects those kind of rides.

Dad isn't friendly terms with the new neighbors, who happen to be clowns. Cow falls in love with the clown son, who in return falls in love with Cow. They play hooky to spend the day together. Dad finds out, and Cow in grounded, while he kicks the clown son out, and chews clown dad out.

Dad tells the story of how he and Mom met to Cow and Chicken.

Red Guy shows up at Cow and Chicken's house, claiming to be a beauty pagent scout. He then dolls up Cow, and enters her into the next beauty pagent. While Cow literally makes a mochrie up on stage, she wins anyway with her inner beauty. Cow then discovers that it was all a scam so Red Guy could wear the tiarara, and hold the roses, at least just once.

When Cow and Chicken get depressed, their parents suggest them to go to a mysterious swamp, and find a blind blues singer to fight their depression.