Charlie puts on a new behaviour, prompted by his fellow friend who is also a patient. Julia spends time with Jeanie, a woman she works with and they talk about their troubled marriages. Bailey wants to bond with Annie's daughter. Julia is surprised when she finds out Jeanie left her husband.

Charlie has some hard time trying to be there for both Owen and Diana. Bailey fights with the owner of a new restaurant. Julia finds out just how bad Ned's relationship with his parents is. Meanwhile, Claudia wants to go home immediately.

A shocked Julia won't talk to anyone about Ned's violent behavior. Griffin tries to get Claudia to join his band, but neglects to asks the other bandmembers. Charlie has a hard time with the fact that Daphne left. Bailey and Sarah are robbed at a restaurant,

Bailey finds out that Owen may have a learning disability. Charlie tries to convince Daphne to return to San Francisco. Julia makes Ned see a psychiatrist after she agrees to stay with him if he gets help. Kirsten moves to Chicago with her parents.

As Sarah and Bailey move back to the Salinger house, Charlie and Kirsten's relationship grows as he moves into her apartment. Julia gets close to a visiting female English professor. Claudia's bandmate tries to reunite her with Cody at an R.E.M. concert.

Charlie and Kirsten have a terrible honeymoon, but when they start to experiment sexually, they end up having a great time. Cody keeps pursuing Claudia, who turns him away. Bailey and Sarah are having communication problems, but are solving them by having sex. Joe tells Bailey about his separation from Frannie. Julia has writers' block.

Bailey goes to a bar and almost drinks, but meets a woman named Tracy, who turns out to be married. Griffin sees Daphne working at a strip club. Bailey invites Will to move in. Myra keeps turning to Charlie for help, but when he reports her principal, Myra's mother claims that he was involved with her sexually. Julia wants to make her and Evan's relationship public, but he becomes very hesitant. Claudia finds out that Cameron got back together with Alexa. So she tries her luck with a football player. But when he gets her alone, he won't take no for an answer.

Bailey goes to a wedding with Holly and all her relatives think they're married. Julia's new editor hasn't answered her about her book, so she tries to find her and not just sit and wait. When she finds her, she tells Julia that another book with the same story of hers has been published, so her book won't be published anymore. Thurber, the family dog, is sick. Claudia takes him to the veterinary. Charlie and Kirsten are in a double date with Daphne. Charlie quits his job after his boss says no to his projects, but when they talk, he gets back. Bailey and Claudia decide to put Thurber to sleep, and the whole family spread his ashes in the park, saying goodbye for the last time to the long-time friend.