After a young, healthy and hunky fireman dies suddenly at Hope Zion Hospital, Alex must take the stand at Hope Zion’s Morbidity and Mortality (M&M) Rounds to find out what went wrong and who is to blame. Meanwhile, Charlie deals with a nervous aspiring Nun, and Joel has to decide if he can be the man that comes through for Sonja.

When Alex is forced to put a patient’s gender reassignment surgery on hold, she discovers a secret in his medical history that could save his surgery, but tear his life apart. Charlie deals with a patient who is healthy, sane – and convinced she is going to die at midnight. Meanwhile, Joel secretly helps Sonja deal with a patient of hers who’s been admitted to Hope Zion Hospital.

Alex encounters a trapped teenager during a hike in the woods; a woman refuses to see anyone but Joel; an exotic dancer comes to the ER.