Lu faces the horrifying memory of her rape when a patient turns to her for help in dealing with her brother, a convicted sex offender. When Andy's patient displays baffling, life-threatening symptoms, Andy suspects foul play.

Dr. Campbell's husband hits her and she kicks him out of their house.

Lu helps a terminally ill patient's family deal with the complicated issues surrounding assisted suicide. Meanwhile, when Andy helps a young couple figure out why they are unable to conceive a child, she stumbles upon a cause that changes their lives forever. As Andy and Milo's relationship becomes serious, he invites her to dinner with his parents. However, Milo's mother, Eve, is less than thrilled with Andy being the new woman in his life.

Andy is considered for the prominent Chief of Surgery position (after the current Chief retires) and discovers a competitor bribing members of the board which is going to decide on a replacement. In the midst of this, she must decide whether or not to perform a potentially career-hurting dangerous surgery on a pregnant woman run over by an SUV driver talking on their cell phone. Meanwhile, Lu battles a company that wants to take her financially-deprived patient's cells to find a cure for leukemia without paying her. Also, Lana finds romance over dog residue.