John «J.D.» Dorian har startet sin legekarriere i et absurd sykehusunivers fylt av uforutsigelige ansatte og merkelige pasienter. Humor og tragedie går hånd i hånd ved Sacred Heart Hospital. Foreldrene til både den ene og den andre dukker opp og skaper noen utfordringer i hverdagen.

Finding difficulties training his interns, J.D. asks to Elliot for some help. She tells J.D. about Sean, who gave Elliot great tips based on his dolphin training that fit perfectly for her interns.

Dr. Cox finds the ideal pediatrician for his son: Dr. Norris, who acts and looks just like him. However, Dr. Cox is quick to find a problem with him once Jack develops a cough that scares both him and Jordan.

Turk and Carla turn J.D.'s old bedroom into a nursery for the baby. The Janitor seizes an opportunity to shove J.D. out of the picture for a day. Elsewhere, Elliot uses her mother to learn information about Keith's peers and Turk & Dr. Cox accuse each other of not being hip.