An obnoxious talk show host known as ""The Peoples' Voice"" begins to receive death threats, and the Chief is assigned to protect him. Firstly he must overcome his own feelings of dislike for the man, but are those feelings entirely misplaced? Events escalate when the host's wife is killed by a car bomb apparently meant for her husband.

Barbara Jones, the amnesiac victim with whom the Chief once fell in love (season one episode Barbara Who), calls Ironside in when her daughter is kidnapped. Not only is it a difficult case, but the Chief has an over eager Sheriff, a jealous husband and his own feelings to contend with, as he attempts to find the girl before it is too late.

The Chief begins to receive strange phone calls, warning him of a murder to be committed somewhere in San Francisco, apparently in the interests of justice. With very little to go on and virtually nothing to help him identify his mysterious caller, Ironside eventually traces the case back to a policeman, thrown out of the force fifteen years earlier.

The Chief is sure that a man just released from prison is responsible for the murder of a policeman, but as determined as he is to prove it, the man in question is equally determined that it will never be proved. With this in mind he persuades a woman of dubious reputation to become close to Ironside, so that she can assassinate him.