A notorious gangster is preparing to turn State's evidence when he is murdered, but Ironside pretends that the man is still alive, and ready to talk, in order to catch the killer and nail a major criminal.

A policeman known to Ironside for some years is shot dead whilst on an investigation. The evidence points to him being crooked, but the Chief is determined to prove otherwise.

Ironside is having problems keeping a group of local kids on the straight and narrow, and enlists the help of football star Bat Masterson, an old friend of Mark's. Bat's brother Joe, however, is a rather less savoury character, and Bat has to choose which side he is on.

An ingenious art theft takes place at Comus Towers Art Museum, and a guard is murdered in the process. Chief Ironside takes the case, but another death is to follow; this time the proprietor of the museum, who is an old friend of the Chief's.

A friend of the Chief's turns out to have been living under an assumed identity for the last nineteen years, and is wanted in New York for murder. The mayor is determined to have him extradited back to NY for execution, but Ironside is equally determined to save him, especially when it becomes clear that he is innocent.

A visiting Soviet athlete vanishes during a practice run, and Ironside is placed on the case. It soon turns out that the 'trustworthy Soviet hero' is anything but, and that the athlete is working for American Intelligence. Has he simply disappeared, however, or has he been found out?

Eve's niece is arrested for possession and use of marijuana, and the Chief investigates her school and friends in a bid to clear her. It soon becomes obvious that she is guilty as charged, but how many others are involved, and just whose fault is it?

A fortune teller predicts various confusing prophecies for the members of Ironside's team, which begin to come true with remarkable accuracy. Faced with a missing Da Vinci painting, a kidnapped Ed Brown, and a prediction of his own death, the Chief has to find out who is responsible, before the visiting French ambassador becomes too upset at the loss of his country's much loved art treasure.

Ed and an old friend uncover a drug running operation whilst having a night on the town, and after becoming implicated in the affair they are suspended. Ed risks extreme wrath from above in order to continue his investigations, whilst the evidence against his friend continues to grow.

A famous baseball player who is an old friend of Ed's begins to receive nuisance mail, which soon turns into something far more sinister. Fearing for his family, he refuses Ed's offers of assistance, and tries to handle the situation alone. Ed has to persuade him to change his mind, before events get out of hand.

Mark's aunt Ruby is cheated out of her life savings by a pair of conmen, and the team set out to capture those responsible. Ed and Eve go under cover as a rich couple, but the investigation is threatened when Ed's cover is blown by a woman he once arrested.

Ironside and Mark travel to France to handle the security for an American delegation at a conference with the Chinese, but somebody is determined to stop the talks from going ahead. Meanwhile, Mark falls in love with one of the Chinese delegates.

Mark encounters a group of freedom fighters at his local college, who appear to have more attitude than sense. When it turns out that they also have a roomful of stolen automatic weapons, the Chief has to decide whether or not they represent a threat to the security of San Francisco.

Taking an important witness from Hawaii to San Francisco by plane, Ironside discovers that a fellow passenger is a hitman. He has to find out who is trying to kill his witness before the plane lands; but there may be more than one person trying to claim the reward for an open contract.

Driving home from a visit to his cousin, Mark picks up a hitch hiker, who turns out to be a thief looking for a scapegoat. The pair become friends, however, which causes problems when her accomplice turns up, anxious to carry out the original plan.

When he arrives in Fiji to spend his holiday with an old friend, the Chief is suspicious about news that his friend has gone to visit him in San Francisco. After sending for Mark and Ed to join him, Ironside himself promptly disappears, leaving the boys to put the pieces together themselves.

An ex-thief on parole is suspected of a jewel robbery, but the Chief, who has supported him since his release, is sure that he is innocent. Of all those with the means to commit the crime however, it seems that only this man and his young cousin are likely suspects. The fate of an entire rehabilitation programme may hang on Ironside's ability to prove his friend innocent.

A thirteen year old boy is the only witness to his mother's murder, but finds it hard to co-operate with the Chief, knowing that it was Ironside who put his father in prison. Allowing Marty Jessup a temporary pass is the only way for the Chief to solve the murder and to lessen his conscience at the same time.

A dog belonging to a rich friend of the Commissioner's goes missing, and Ironside is assigned to the case. Somewhat scornful of the task, he details Ed and Eve to investigate instead; but is soon lured back when, helped by Mark, they uncover a racket stealing dogs for ransom.

The Chief begins to receive strange phone calls, warning him of a murder to be committed somewhere in San Francisco, apparently in the interests of justice. With very little to go on and virtually nothing to help him identify his mysterious caller, Ironside eventually traces the case back to a policeman, thrown out of the force fifteen years earlier.

The Chief travels into the mountains to spend the weekend with an old friend, only to be snowed in following a bad blizzard. Trapped in a small cabin, Ironside discovers that his friend is now an addict, violent and unpredictable without the fix he cannot get.

Due to give evidence, the Chief discovers that there is a contract out on his life, and that the chosen killer is a highly dedicated man. Whilst the authorities see only the lethal killer, however, it seems that everybody has another side to their personality.

After the murder of Police Captain Belding, his daughter, a rookie cop, is anxious to prove that the allegations of corruption against him were false. She hampers the Chief's investigations and generally gets in the way, but he takes a shine to her, and has her drafted onto the team.

A prisoner is denied parole for no clear reason, and the Chief's investigations lead him to a woman who seems to have supernatural powers. With his team clearly taken in by the apparently inexplicable events going on, Ironside has his work cut out trying to find a rational explanation.

An actor/producer is murdered during a series of comic improvisations, and all of the actors present at the time seem to be suspects. Given a number of aliases and false leads, the Chief embarks on the trail of the killer.

A string of murders is committed, and in each case the victim has a numbered disk in their possession. After number four is found dead, it transpires that the Commissioner is the owner of disk number six; and the Chief disguises himself as number five - an irascible artist to whom he bears a striking resemblance - in order to keep him alive.

When her fiancé is accused of murder, a young woman comes to Ironside for help; but when it transpires that the fiancé in question is an old Naval acquaintance of the Chief's, a man with whom he did not get along, the assistance is both offered and accepted somewhat grudgingly. It soon becomes clear, however, that the prejudice which exists in the couple's home town is in serious danger of destroying an innocent man's life.

A returning Vietnam vet sees his supposedly dead father at the airport, and initiates a search for him against the Commissioner's wishes. The father, a one time member of the SFPD, turns out to be in hiding from a crime family eager to kill him for his part in their downfall, and the last thing that he wants is to be found.

Ed gets grounded in Reno whilst transporting a murder suspect back to San Francisco, and knowing gunmen to be on his tail he hides out in an abandoned bar to await assistance from the Chief. As he soon discovers, however, there are other dangers besides hit men for him to worry about, before he can meet up with his colleagues and deliver his prisoner to jail.

A man dies of a heart attack whilst flying his plane, but the town medical examiner, a charmingly eccentric Cuban doctor, is convinced that there was foul play. By chance Ironside and Ed are on their way to visit and soon become involved in his investigations; but between pregnant ducks and volatile banana cocktails they have their work cut out as never before.

When somebody takes pot shots at Fran's hot-headed cop boyfriend, he soon comes under suspicion for a handful of assaults and two murders. All the trouble seems to be linked back to a case he investigated with his one-time partner, now turned private eye; but is it a case of cop-turned-bad, or is it something else?

A friend of Ed's becomes the target of an assassin, but cannot shed any light on the reasons for the attempt on his life. When Ed discovers that his friend is a priest, prevented from speaking by the bounds of confession, he and the Chief attempt to discover the truth; which soon leads them to three unexplained murders amongst the city's drug dealers.

A British police inspector visits San Francisco for a conference, and whilst there assists his old friend Chief Ironside with an awkward investigation. It soon appears, however, that he knows more about the case than he should do, and that his involvement may have something to do with his deteriorating state of health.

Ed befriends the daughter of the judge presiding over his latest case, only for the girl to come to him in fear for her father's life. It seems she is overreacting to a series of accidents, but events soon suggest her suspicions may be correct; especially after it turns out that her father's new wife has old Underworld connections she thought she had left behind.