Romano forces Benton to choose between the trauma and cardiothoracic fellowships. Carol worries that she may have lost her child. Corday and Greene bond on the way to a medical conference. Carter mentors an aspiring teenager. Lucy, on a psychiatry rotation, treats an overmedicated foster child. Jeanie finds her faith while treating a reverend.

Carol's pregnancy becomes public knowledge as she learns that she's having twins. Lucy has problems trying to go off Ritalin. Peter learns Carla plans to move to Germany. Kerry finds an abandoned youngster and brings him to the ER. Mark and Elizabeth discuss their relationship. Jeanie and Reggie draw closer again.

When Anspaugh decides to retire as chief of staff and return to surgery, he appoints Romano as his replacement. Greene expresses reservations about the decision, but Weaver does not support Greene. Romano makes Weaver the new chief of emergency medicine.

A recommendation from Weaver allows Jeanie to have temporary approval as a foster parent for baby Carlos. Reggie and Jeanie get married. Lucy and Kovac talk with a young woman whose husband they believe is very dangerous.

Carter and Lucy are discovered and the staff struggles to save them and go on with normal patient care.

Carter seeks psychiatric help because he can't sleep. He then visits the wife of his attacker. Weaver returns to work after her suspension. Hathaway and Kovac share a kiss.

Weaver reprimands Carter for doing a dangerous procedure without consulting Kovac. She also talks to Hathaway about Hathaway's lack of focus on the job. And while treating a 6-year-old patient involved in a minor car accident, Malucci and Cleo discover the girl has been sexually molested recently by her father.

As the result of a school shooting, Kovac and Benton care for the gunman and his victims. Abby discovers that Carter has been illegally injecting pain relievers. Greene and Weaver confront Carter about his problem, and Weaver orders him to enter a drug rehabilitation center or leave the hospital permanently.

Maggie contests Abby's attempt to institutionalize her. Weaver treats a few bizarre patients. When Legaspi returns to work after being exonerated of sexual harassment, Weaver tries to reconcile with her. Benton injures his hand while transporting his former teacher to the hospital and must contend with the teacher's wisecracking elderly buddies.

Dr. Pratt brings a gun into the ER; Dr. Weaver tries to conceal her pregnancy; a woman plots against her dying husband; Dr. Chen treats math students who overdosed on an unknown stimulant.