Dr. Hicks berates Benton when he tries to switch shifts to attend his mother's birthday party. A teenage girl, a frequent patient of the ER, is brought in for a drug overdose. Carol decides she wants to adopt Tatiana while Tag isn't so sure. Dr. Ross slugs an abusive father in the lobby. Jen accepts a job offer in Milwaukee despite Mark's offer from Morganstern. Deb and Carter await the arrival of sub-internship applications.

Susan is forced into the role of parent when Chloe gives birth and both Chloe and her mother, Cookie, shirk responsibility. Doug is surprised and a bit frightened when Diane suggests they move in together. Unfortunately, Linda Farrell happens to be around to take advantage of his nervousness. Carter is offered the ER sub-I but turns it down in anticipation of receiving a surgical position. Peter receives unpleasant news; his mother has died.

Weaver returns to the emergency room after a self-imposed sabbatical of three weeks, wondering how her newfound lesbian identity will affect her workplace relationships. Having purposely allowed a mass murderer to die, Greene must keep the secret amidst the scrutiny of his superiors.