Betty takes a break from her escalating family troubles when she's assigned to review a posh new hotel. Meanwhile, Daniel is dismayed when Sofia Reyes and her team take up residence in the Mode conference room, and Wilhelmina goes a little bit country to woo a mega rich Texan to advertise his stores in Mode.

To his dismay, Daniel must attend his family's Thanksgiving gathering at the Country Club. Meanwhile, Amanda and Marc create their own gathering at Mode and there is also a dinner at Betty's house where Santos, Justin's father, is in attendance. Meanwhile, Wilhelmina also hosts a Thanksgiving dinner as well but her feast doesn't look as good as it does in magazine pictures.

Betty is left alone during an important photo shoot during which the photographer, Bruno, has come up with questionable concepts. Meanwhile, Daniel wants people to believe he is a family man, Mr. Green interrogates a mortician about the remains of a client and Ignacio gets in trouble with Immigration and Customs.

Alexis' shocking announcement causes great commotion at both Mode and the Meade home. Betty tries to maintain the peace and order at Mode, however, she is about to face her own personal turmoil when Henry asks her out on a date and Walter tells her he's got a big surprise in store. Meanwhile, Whilhelmina plots her next move to conquer Mode and Justin gets sent home from school for fighting.

Daniel reconnects with Grace Chin, a girl he once stood up for a date in college, and who is now New York City's top lawyer. Meanwhile, Betty befriends Charlie, an out-of-towner she meets at the Mode cafeteria, whom she later discovers to be Henry's girlfriend.

After seeing her working relationship with Daniel, her close friendship with Christina, and her chance to date Henry all fall apart, Betty is left with no choice but to turn her back on all three. Meanwhile, romance is in the air: At MODE, Alexis catches the attention of a guy and he asks her out; Amanda flirts with a designer who she believes is gay; and Wilhelmina finds her latest advances very tiring. Over at the Suarez's, Santos gives Hilda a little surprise.

Betty and Henry's romance heats up. Meanwhile, Wilhelmina makes great strides in her ambitious power play, as Daniel descends further in a downward spiral. The Suarez family trip to Mexico takes a dangerous turn, with old ghosts creating new problems. Explosive secrets will be revealed, and everything will be tied together by a beloved Broadway musical.

Betty's life is turned into turmoil after the numerous upsetting events that have recently occurred. Despite all this, she refuses to accept the fact that Henry's leaving has deeply affected her. Meanwhile, Amanda has a hard time coping with the news she recently discovered about who her real mother is and Wilhelmina plans to use all the recent tragedies to her advantage.