After a despondent woman takes a walk off of an eight-story apartment building, the squad finds themselves in a race to transport both the woman's heart and a dying girl to a local hospital in time to save the youngster's life. The suicide hits home for Faith as she comes to grips with her own ongoing medical problems, while Doc expresses concern over the emotional effects this case will have on Kim, despite her constant reassurance that her accident was not an attempt to kill herself.

Jimmy and Kim, still locked in a custody battle over Joey, meet with a court-appointed evaluator and plead their cases in a heated exchange.

When Sully and Tatiana visit his mother at her nursing home, Tatiana expresses concern over the quality and cost of his mother's care. Convinced that she can do a better job of taking care of her at home, she signs her out and moves her in with them. Sully is shocked and displeased, and tells Tatiana that it will be too difficult for her to take care of his mother.

Alex tries to stay busy to avoid dealing with her feelings about her father's death. Eager to fill empty hours and maintain the brave front her father insisted upon when she was growing up, she works extra shifts and even helps Carlos and Ty move into their new apartment. While Carlos is downstairs unloading the truck, Alex takes Ty up on his previous offer to talk and asks him about his father, who also died in the line of duty.

Bosco's emotional turmoil escalates when he begins to experience panic attacks and flashbacks, but continues to deny that there's anything wrong. After he has a panic attack while driving the patrol car and nearly causes a crash, Sully insists that Bosco see his friend Brian O'Malley, who's a therapist and a former cop.

Bosco gets a temporary assignment working with a tough female sergeant; Fred is strangely calm in the face of the prospect of a triple bypass; Doc hears shocking news from Philadelphia; Sully learns more about Tatiana's past; Davis is forced to deal with his newfound fame.

When a fire breaks out in the supermarket where Bosco and his mother Rose are doing some late night shopping, Bosco rescues most of the shoppers but cannot save a young mother when she goes back inside to retrieve her purse. After Jimmy tells him that the fire was probably deliberately set, Bosco is convinced that he saw the arsonist in the crowd outside after the fire. Sgt. Cruz gets Bosco and Faith assigned to the Anti-Crime Unit for a few days so that they can track the guy down. At the scene of another supermarket fire the next night, Faith takes down license plate numbers, Cruz photographs the crowd and cars at the scene, and Bosco nabs the man he saw in the crowd the night before. The man turns out to be a fire buff, but Faith and Cruz's work bears fruit and they find their arsonist -- the son of Doug Maple, an NYFD arson investigator. A depressed Sully is still on leave, drinking too much, and sleeping on the couch at Ty's and Carlos' apartment; Doc connects with an attractive

Sully's stopped drinking, but his poor attitude remains; Carlos gives his two week notice; a blizzard blankets the city and the squads are called in early; an understaffed Doc defies orders and puts Carlos back on the street as the squads are kept busy rescuing victims of the storm; Faith's initial wariness about Emily's new boyfriend Eric turns out to be well-founded when he is brought into Mercy after an overdose of Special K, but doesn't remember where he left Emily after she also got high; Faith, Bosco, Sully, Ty, Doc and Carlos go out to search for Emily, and rush her to Mercy after she's found in critical condition; Faith and Fred blame each other for letting Emily go out with Eric.

In a last-ditch effort to save Sully's life, job, and pension by getting him dried out, Ty and Bosco kidnap him and bring him to a cabin deep in the woods where he hallucinates about the circumstances surrounding the deaths of Tatiana, Chevchenko and Ty's father, and his subsequent descent into alcoholism.

Cruz's desire to find the ring leader of the Meth ring puts Bosco in a uncomfotable position. Faith tries to improve her relationship with Emily and also gets a new partner, Sasha, at work. Noble is released and sets up a new date with Kim.

On his last day on the street, Doc's guilt and grief over Alex's death emerges as anger towards everyone he encounters, especially Eugene, the new paramedic trainee whose place Alex took the day she died; Kim becomes frantic as she fears that she have been exposed to HIV after having unprotected sex with a drug addicted Noble, and Jimmy agrees to accompany her when she gets tested; Swersky goes to bat for Faith by creating the opportunity for Bosco to talk to her before she's interrogated by I.A.B.; Carlos is less than thrilled when he discovers that Kim is the new supervising paramedic and Jimmy has been promoted to take over Lt. Johnson's position; Bosco returns to work and faces a hostile reception from the squad for ratting out Maritza; Faith awakes to discover that she's paralyzed; Maritza refuses to let Faith off the hook for shooting her until Bosco tricks her into recanting her story; Faith thanks Bosco for keeping her out of jail and saving her job, and then tells him to get l

Barbara is heartbroken when she discovers that her housekeeper was killed by the explosion; Sasha convinces Maritza to get a rape exam; Sully takes Barbara to his house to keep her safe; Maritza discovers that her rapist, Thomas Warner, has a history of sexually assaulting the workers at the clinic; undeterred by yet another attack on her life, this time by a sniper, Barbara insists on presiding at the preliminary hearing of Gary Barnes, the drug dealer who the police suspect is behind the attempts on her life; Faith visits a psychiatrist and unloads her anger at Bosco and Maritza; after Maritza testifies at the hearing, Barbara rules that Barnes can be held over for trial for the death of Lettie Cruz; when Sully sees Barnes signal a spectator in the court room, he and Ty follow him to a house where they see him join the man who delivered the bomb to Barbara's house; the perps, armed with a detonator, threaten to blow up the block with the explosives they claim are in the house and for

Steeper exiles the paramedics to permanent fixed posts on the street, which upsets everyone on the squad except Doc, who refuses to let anything put a damper on his unusually upbeat attitude; Carlos is less than thrilled when Doc invites Christian to accompany them on a ride-along without getting the proper authorization; when Bosco goes after Nardo for his veiled threats against Rose, Nardo tries to set Bosco up to look like a dirty cop; Rose is fired after Bosco destroys poker machines owned by Nardo in the bar where she works; on the eve of her return to duty, Faith tells Bosco that she wants to repartner with him; Sasha's second thoughts about the plan she and Bosco hatched to repay Nardo for threatening Rose and attempting to frame Bosco turn out to be on target when Nardo flees after murdering two men; Doc and Sasha hook up after Doc throws a big party at his house for his co-workers.

The Boscorelli family suffers a tragic loss at the hands of Donald Mann, who blames Bosco, Faith and Maritza for the death of his son in a high-speed chase; the Yokas family heads off in different directions; the Martin family splits apart into separate jail cells for the parents, and a return home for Rebecca to the mother from whom she was stolen as an infant; the paramedic family at the 55 gets a new member, Grace Foster, which makes no one involved very happy.