Claire and Jamie visit his Aunt Jocasta at her plantation, River Run. When tragedy strikes at the plantation, Jamie and Claire find themselves caught between what's right and the law of the land.

Jamie and Claire search for a place to call home. Meanwhile, in the 20th century, Brianna and Roger's romance heats up and then fizzles during a road trip that winds up highlighting their differences.

Jamie and Claire keep secrets from one another as they try to help Brianna process her recent trauma. But the secrets they keep cause a bigger familial rift once they are revealed.

Jamie, Claire and Young Ian embark on a long uncertain journey to rescue Roger, while Brianna forges a friendship with one of Jamie's old friends as she fends off Aunt Jocasta's attempts to secure a husband.

Jamie, Claire and Young Ian's attempt to rescue Roger from his Mohawk captors goes awry when a ghost from Claire's past lays waste to their plan. Meanwhile, Brianna worries Claire, Jamie and Roger might not return.