Detective Barnaby Jones comes out of retirement to solve his son's murder with some help from fellow detective Frank Cannon.

An affair leads to an accidental murder.

Barnaby's investigation into the disappearance of a young girl hinges on a roommate who may have witnessed what happened to her. But the roommate herself now suffers from hysterical blindness because of the traumatic event. Barnaby must find a way to crack the case before the roommate becomes the next victim.

At the request of his late son Hal's friend, Barnaby investigates a lodge owner who is suspected of murdering his wife. Even though he finds conclusive evidence to exonerate the man, Jones suspects that all is not as it appears.

While investigating the death of a man bitten by a rattlesnake, Barnaby soon suspects that there is more than one snake involved...and it's one that wears cowboy boots and has a prison record.

A detective friend of Barnaby who is intent on catching a murderer, has been receiving letters from the man who is taunting him. But when he gave him too much information the man kills him and Barnaby sets out to find him.

Barnaby investigates a jealous husband who he believes murdered a man for having an affair with his wife. But did he murder the wrong man?

A man dies under suspicious circumstances after being warned by a psychic and Barnaby Jones is hired to investigate. Barnaby doesn't buy the psychic mumbo-jumbo and suspects that once again money is at the root of all evil.

The owner of a basketball team is informed that his star player once threw a game. The person who told him that, wants him to make sure that his team loses a game. So the owner kills him. Barnaby is hired by the man's wife who is the sister of the player to find him.

Barnaby is hired to find a missing writer and gets caught between a man with a story to tell and mobsters who don't want his tell all book written.