Harry becomes an overnight father figure to nine-year-old Billy and teenage Anastasia, who both seem to be the product of Harry's past foray into sperm donation. Meanwhile Harry meets Rose, a beautiful, if neurotic, single woman who's out to have a baby on her own, and who believes Harry may have what she needs to get pregnant.

Harry helps Billy’s moms, Zoey and Michelle, to encourage Billy to be cooler at school. Meanwhile Jonathan and Janet fear their daughter Anastasia may be failing French, and administer an I.Q. test to Harry, fearing she got the ‘dumb gene’ from him. Harry and Rose square off about the future of Rose’s potential child.

Double-booked, Harry must decide between scoring with a hot fashion model or attending his baby's first ultrasound.

Harry helps Billy become his school’s top charity salesman, while Rose tests her maternal instincts on an electronic baby.

Rose hides her pregnancy from her boss, while Harry discovers the truth about Jonathan and Janet's sex life.

Harry figures out the secret behind Rose’s new boyfriend, while Zoey and Michelle deal with consequences of Billy having lice.

When Janet diagnoses Harry with Sympathetic Pregnancy, Rose finds that she’s competing for sympathy with her new, narcissistic belly-buddy, Harry. Meanwhile Zoey and Michelle rejoice after finding a babysitter (Leah Feidh Fassett) Harry can’t hit on – because she’s a lesbian. Janet discovers Jonathan has been seeing another therapist behind her back, Dr. Meinertzhagen (guest star Tom Green).

Harry helps Rose to make friends in her new birthing class, while Janet and Jonathan fight for the chance to be involved in Anastasia's prom.

Harry coaxes out Rose's bachelor side when they are forced to share an apartment. Zoey's grandmother plays a visit, and Rachel goes behind Jonathan's back in an attempt to get a good deal on a car.

Harry lies about having a relationship with Rose to score with a home-wrecker; Jonathan and Janet attempt to connect with Anastasia online.

Rose lies to make a preschool waitlist; while Zoey and Michelle attempt to give Billy 'The Talk'

Roses's pregnancy nears full term, prompting Zoey and Michelle to contemplate whether they will ever want another child of their own.