The heinous Him toys with Bubbles' mind by speaking to her through Octi, her favorite stuffed animal. Following Octi/Him's instructions, Bubbles provokes a fight between her sisters that prompts the Professor to issue a time-out until the Girls can make amends and make squid meat out of the giant, Him-controlled Octi.

The Amoeba Boys' ill-conceived plan to stand in front of the "Keep off the Grass" sign at Townsville Park all night in the rain leaves them with a terrible virus. When they infect the Townsville population, it's up to the Girls to find the antidote.

The Powerpuff Girls play baseball and the ball goes into Mojo's home. They ask him to look for the ball, but Mojo takes advantage of the situation and tries to destroy them.

A clown get's hit by a bleach truck and turns into an evil mime.