The governor calls on Team Scorpion when his daughter is mysteriously "bio-hacked" with a deadly virus and only has 24 hours to live. The case takes on a deeper significance for Walter after he receives a letter regarding his sister.

When Sylvester accidentally triggers an explosive device during an investigation, Team Scorpion must focus on finding who's responsible even while their friend's life hangs in the balance.

To protect a key witness who is en route to testifying against a deadly drug cartel, Team Scorpion takes her on the run, with the cartel hot on their heels.

Walter, Cabe and Happy are trapped with the crew in a top secret submarine when an explosion sends it to the bottom of the ocean with limited oxygen and a self-destruct function that will soon activate.

The members of Team Scorpion brave subzero temperatures in Antarctica to save a United States Special Forces unit. Toby risks his life to save Happy.

While on a secret mission in Djibouti, Africa, with his new Homeland protégé, Tim Armstrong, Cabe is captured and Team Scorpion must save him.

Before Halloween, Team Scorpion must infiltrate a deep, vast cave system in order to prevent a bat population from destroying the North America ecosystem. Also, the team dons costumes to stage photos from Halloween’s past for Walter’s upcoming immigration inspection.

When a mission in the desert results in exploding shrapnel that seriously wounds Cabe, Team Scorpion must freeze his body in order to save his life.

Team Scorpion must defy the orders of a foreign government after they retrieve an asteroid from space containing DNA strands that could have deadly consequences once exposed.

When poachers almost kill a pregnant endangered deer, Team Scorpion recreates the animal’s womb to try to save it and its baby’s life. Also, Happy and Toby discuss the future of their family.

As Team Scorpion anxiously awaits the verdict of Cabe’s trial which could send him to prison, they focus their nervous energy on trying to save a dog stuck in a cistern.