Medical resident Liv Moore becomes a zombie and loses her ambition until she begins working at the city morgue to gain access to brains that give her sustenance and allow her to maintain her humanity. She also learns that her new diet enables her to experience a victim's memories that can be used to help solve the person's murder.

After eating the brain of their newest John Doe, Liv gets a vision of Clive as a dirty cop working with a gang to find a rat in their organization. Meanwhile, Major gets a new roommate, and Blaine expands his business operation.

Lt. Suzuki dedicates all of the police resources to finding the killer of a rich white girl who died of exposure after an eight-month disappearance. The girl gives birth before she dies, and Liv soon starts having maternal feelings toward the baby and everyone else around her. Meanwhile, Major tries to find out more about Julien, and Liv and Lowell's relationship changes when he eats the wrong brain.

Four teenagers hit Sebastian shortly after he becomes a zombie, and he kills one of them. When the body turns up, Liv eats the brain and tries to find out who is responsible. Meanwhile, Ravi and Peyton plan a trip to San Francisco, but Liv gets a visitor who interrupts their plans.

As Liv and Clive try to track down Cameron and determine his connection to Max Rager, Blaine interrogates Major about the missing brains.

Liv consumes the brains of a cantankerous old man to help gain insight into his death. After receiving an anonymous call on the tipster hotline, Liv and Detective Babineax stop by the residence of Byron Thistlewaite, to question the mysterious caller. Meanwhile, Ravi suspects that Major might be experiencing a side effect of the cure, and Liv pays Blaine a surprise visit.

Liv and Clive investigate the murder of Miss Teen Seattle beauty pageant contestant, Laurie-Beth Spano, who went into anaphylactic shock onstage in 1999 and ended up in a coma. At the time, police arrested rival contender Velma Charlet for spiking Laurie-Beth's makeup and she was given a four-year sentence. In present day, Laurie-Beth has passed away and Clive has arrested Velma, for her murder. Velma claims to be innocent and Liv consumes Laurie-Beth's brain in hopes of tracking down the murderer.