A ruthless defense attorney and no-nonsense law professor at a Philadelphia university selects a group of her best students to work at her firm.

Annalise takes on a new client, Max St. Vincent, an eccentric millionaire who is the key suspect in his wife's brutal murder. All the clues point to St. Vincent as the killer, but Annalise challenges her students to prove he's innocent - whether that's the truth or not. Meanwhile, Annalise deals with issues in her own home when her growing suspicions that Sam is somehow involved in Lila's disappearance start to affect their marriage. In flash forwards, we go back to the night of the murder and learn that Wes might be hiding a few secrets of his own.

Wes, Connor, Michaela and Laurel may have dug themselves in too deep a hole for Annalise to save them, and the shocking truth about Lila's murder is finally revealed.

Annalise and her students must move on with their lives as though nothing has happened, but the students are still reeling over Rebecca’s disappearance. Only Annalise and Frank know that Rebecca was murdered and the two are determined to find out who killed her. Meanwhile, Annalise decides she wants to take on a new client, a brother and sister who are accused of killing their parents. And an old friend surprises Annalise at home and teaches her a valuable lesson.

Annalise begins to crack under pressure and wants to leave. Frank has to try and accept the things he has done.

With Wallace Mahoney’s murder unsolved and Frank’s whereabouts unknown, the "Keating 5" struggle to move on with their lives as they enter into their second year of law school. Meanwhile, Annalise’s reputation at Middleton University is on the line, so she creates a criminal law clinic where the students will compete to try their own pro bono cases. Annalise also wrestles with a decision involving Frank that could change everything.

Annalise and the Keating 4 test the limits of how far they’ll go to save themselves while the chilling details from the night of the fire reveal who killed Wes.

In the wake of Wes’ tragic death, Annalise returns to her family home to pick up the pieces of her shattered life, and realizes that, in order to rebuild, she must make a tough and shocking decision. Meanwhile, “the Keating 4” all face an uncertain future while Laurel becomes obsessed with finding out what actually happened to Wes the night he died. In a flash-forward, a terrifying crime is committed and everyone is a suspect.

Annalise and her inner circle deal with the aftermath of a suspicious death that culminates with a shocking arrest; a new development involving one of their own changes everything.

Annalise selects students for her new legal clinic at Middleton and juggles job offers from competing firms, all while the Keating 4 attempt to move on from last semester’s turmoil. And in a startling flash-forward, a new mystery is introduced and it shakes things up for everyone.

Annalise discovers there’s a surprise witness that threatens her case. Meanwhile, Connor tries to persuade the K3 to go along with a new plan. Elsewhere, a lie between Frank and Bonnie threatens their relationship as Annalise’s killer is finally revealed.